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1/2024
vol. 89 Technology and contrast media
abstract:
Review paper
The use of intravascular contrast media in patients with impaired kidney function – joint clinical practice position statement of the Polish Society of Nephrology and the Polish Medical Society of Radiology
Michał Chmielewski
1, 2
,
Zbigniew Serafin
3
,
Dorota Kamińska
4
,
Katarzyna Skrobisz
5
,
Oliwia Kozak
5
,
Piotr Olczyk
4
,
Przemysław Rutkowski
6
,
Marcin Adamczak
7
,
Edyta Szurowska
5
,
Magdalena Krajewska
5
Pol J Radiol 2024; 89: e161-e171
Online publish date: 2024/03/21
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Radiological procedures utilising intravascular contrast media (ICM) are fundamental to modern medicine, enhancing diagnostics and treatment in diverse medical fields. However, the application of ICM has been constrained in patients with compromised kidney function due to perceived nephrotoxic risks, called contrast-induced nephropathy or contrast-induced acute kidney injury. Historical evidence marked ICM as a possible contributor to kidney damage. This led to restrictive guidelines advocating limited ICM use in patients with impaired renal function, preventing crucial radiographic interventions in patients with acute kidney injury (AKI) and chronic kidney disease. Recent advances challenge these traditional views. In particular, no direct causal relationship has been confirmed between contrast administration and elevated serum creatinine concentrations in humans. Furthermore, contemporary research models and meta-analyses do not associate AKI with contrast usage. This paper, prepared by a cross-disciplinary team of nephrologists and radiologists, presents updated guidelines for ICM application amid renal function impairments, emphasising the reduced nephrotoxic risks currently understood and loosening the previous restrictive approach in patients with renal dysfunction.
keywords:
intravascular contrast media, chronic kidney disease, acute kidney injury, position statement |