Central European Journal of Immunology
eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
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4/2007
vol. 32
 
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Clinical guidelines
Prevention of infection in patients with an absent or dysfunctional spleen

Bożena Mikołuć
,
Ewa Bernatowska
,
Radosław Motkowski
,
Barbara Pietrucha
,
Beata Wolska-Kuśmierz
,
Małgorzata Pac
,
Magdalena Kurenko-Deptuch

(Centr Eur J Immunol 2007; 32 (4): 216-220)
Online publish date: 2007/12/10
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An impairment of all spleen functions is a matter of course in both congenital asplenia and asplenia caused by an injury to the spleen. There also exists a group of diseases which result in asplenia or functional hyposplenia. Absence or dysfunction of the spleen brings a higher risk of life-threatening infection. Preventive procedures for patients with congenital, acquired or functional asplenia involve three basic types of activity: vaccinations, chemoprophylaxis, and educating patients, their parents and medical personnel. In this paper we present recommendations for prevention of life-threatening infections in this group of patients.
keywords:

asplenia, immunization, prevention

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