<br>Clinical guidelines<br>Risk of BCG infection in primary immunodeficiency children. Proposal of diagnostic, prophylactic and therapeutic guidelines for disseminated BCG based on experience in the Department of Immunology, Children’s Memorial Health Institute in Warsaw between 1980-2006

Ewa Bernatowska; Beata Wolska-Kuśnierz; Małgorzata Pac; Magdalena Kurenko-Deptuch; Barbara Pietrucha; Zofia Zwolska; Barbara Piątosa; Kazimierz Roszkowski; Bożena Mikołuć; Maja Klaudel-Dreszler

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ISSN: 1426-3912

Central European Journal of Immunology

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4/2007
vol. 32

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abstract:

Clinical guidelines
Risk of BCG infection in primary immunodeficiency children. Proposal of diagnostic, prophylactic and therapeutic guidelines for disseminated BCG based on experience in the Department of Immunology, Children’s Memorial Health Institute in Warsaw between 1980-2006

Ewa Bernatowska

,

Beata Wolska-Kuśnierz

,

Małgorzata Pac

,

Magdalena Kurenko-Deptuch

,

Barbara Pietrucha

,

Zofia Zwolska

,

Barbara Piątosa

,

Kazimierz Roszkowski

,

Bożena Mikołuć

,

Maja Klaudel-Dreszler

(Centr Eur J Immunol 2007; 32 (4): 221-225)

Online publish date: 2007/12/10

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AMA

Bernatowska E, Wolska-Kuśnierz B, Pac M, et al. Clinical guidelinesRisk of BCG infection in primary immunodeficiency children. Proposal of diagnostic, prophylactic and therapeutic guidelines for disseminated BCG based on experience in the Department of Immunology, Children’s Memorial Health Institute in Warsaw between 1980-2006. Central European Journal of Immunology. 2007;32(4):221-225.

APA

Bernatowska, E., Wolska-Kuśnierz, B., Pac, M., Kurenko-Deptuch, M., Pietrucha, B.,  & Zwolska, Z. et al. (2007). Clinical guidelinesRisk of BCG infection in primary immunodeficiency children. Proposal of diagnostic, prophylactic and therapeutic guidelines for disseminated BCG based on experience in the Department of Immunology, Children’s Memorial Health Institute in Warsaw between 1980-2006. Central European Journal of Immunology, 32(4), 221-225.

Chicago

Bernatowska, Ewa, Beata Wolska-Kuśnierz, Małgorzata Pac, Magdalena Kurenko-Deptuch, Barbara Pietrucha, Zofia Zwolska,  and Barbara Piątosa et al. 2007. "Clinical guidelinesRisk of BCG infection in primary immunodeficiency children. Proposal of diagnostic, prophylactic and therapeutic guidelines for disseminated BCG based on experience in the Department of Immunology, Children’s Memorial Health Institute in Warsaw between 1980-2006". Central European Journal of Immunology 32 (4): 221-225.

Harvard

Bernatowska, E., Wolska-Kuśnierz, B., Pac, M., Kurenko-Deptuch, M., Pietrucha, B., Zwolska, Z., Piątosa, B., Roszkowski, K., Mikołuć, B.,  and Klaudel-Dreszler, M. (2007). Clinical guidelinesRisk of BCG infection in primary immunodeficiency children. Proposal of diagnostic, prophylactic and therapeutic guidelines for disseminated BCG based on experience in the Department of Immunology, Children’s Memorial Health Institute in Warsaw between 1980-2006. Central European Journal of Immunology, 32(4), pp.221-225.

MLA

Bernatowska, Ewa et al. "Clinical guidelinesRisk of BCG infection in primary immunodeficiency children. Proposal of diagnostic, prophylactic and therapeutic guidelines for disseminated BCG based on experience in the Department of Immunology, Children’s Memorial Health Institute in Warsaw between 1980-2006." Central European Journal of Immunology, vol. 32, no. 4, 2007, pp. 221-225.

Vancouver

Bernatowska E, Wolska-Kuśnierz B, Pac M, Kurenko-Deptuch M, Pietrucha B, Zwolska Z et al. Clinical guidelinesRisk of BCG infection in primary immunodeficiency children. Proposal of diagnostic, prophylactic and therapeutic guidelines for disseminated BCG based on experience in the Department of Immunology, Children’s Memorial Health Institute in Warsaw between 1980-2006. Central European Journal of Immunology. 2007;32(4):221-225.

The increasing number of reports of disseminated BCG infection (BCG-itis) is very serious, and is almost always in children with immunocompromising conditions such as HIV, SCID, or with another severe form of congenital immunodeficiency. Vaccination at birth is a constant element of vaccination programmes in Central and Eastern Europe, due to the high prevalence of tuberculosis. Difficulties in the diagnosis and therapy of BCG infections in primary immunodeficiency patients, hospitalised in the Department of Immunology, Children’s Memorial Health Institute in Warsaw, during the last 25 years have recently been published in Emerg Infect Dis 2007; 13(5): 799. Based on our experience, we would like to propose a set of novel criteria for diagnosis and prophylaxis, and therapeutic guidelines for BCG infection.

keywords:

Clinical guidelinesRisk of BCG infection in primary immunodeficiency children. Proposal of diagnostic, prophylactic and therapeutic guidelines for disseminated BCG based on experience in the Department of Immunology, Children’s Memorial Health Institute in Warsaw between 1980-2006

Ewa Bernatowska , Beata Wolska-Kuśnierz , Małgorzata Pac , Magdalena Kurenko-Deptuch , Barbara Pietrucha , Zofia Zwolska , Barbara Piątosa , Kazimierz Roszkowski , Bożena Mikołuć , Maja Klaudel-Dreszler

disseminated BCG infection, primary immunodeficiency

Clinical guidelines
Risk of BCG infection in primary immunodeficiency children. Proposal of diagnostic, prophylactic and therapeutic guidelines for disseminated BCG based on experience in the Department of Immunology, Children’s Memorial Health Institute in Warsaw between 1980-2006

Ewa Bernatowska

,

Beata Wolska-Kuśnierz

,

Małgorzata Pac

,

Magdalena Kurenko-Deptuch

,

Barbara Pietrucha

,

Zofia Zwolska

,

Barbara Piątosa

,

Kazimierz Roszkowski

,

Bożena Mikołuć

,

Maja Klaudel-Dreszler