eISSN: 1897-4309
ISSN: 1428-2526
Contemporary Oncology/Współczesna Onkologia
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SCImago Journal & Country Rank
3/2018
vol. 22
 
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abstract:
Case report

A malignant astrocytoma with uncommon angiocentric features and dot-like EMA expression

Wojciech Kuncman
,
Marcin Braun
,
Łukasz Kuncman
,
Piotr Kupnicki
,
Michał Piotrowski
,
Dorota Jesionek-Kupnicka
,
Radzisław Kordek

Contemp Oncol (Pozn) 2018; 22 (3): 205-208
Online publish date: 2018/09/30
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Angiocentric features are uncommon in high-grade World Health Organisation (WHO) brain tumours, whilst they are typical for WHO grade I tumours, e.g. angiocentric gliomas. We present an unusual glial tumour that occurred in a 59-year-old man. The tumour had equivocal radiologic and histopathologic features, especially a characteristic angiocentric pattern, low-to-moderate Ki67, and dot-like epithelial membrane antigen expression. The tumour did not show features characteristic for glioblastoma; however, it recurred as glioblastoma four months later. Based on this case, we show that high-grade WHO brain tumours may show an angiocentric pattern typical for low-grade WHO brain tumours, such as angiocentric gliomas.
keywords:

angiocentric glioma, glioblastoma, anaplastic astrocytoma, ependymal differentiation, angiocentric features

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