eISSN: 2300-6722
ISSN: 1899-1874
Medical Studies/Studia Medyczne
Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
4/2021
vol. 37
 
Share:
Share:
abstract:
Review article

A review of the mechanisms and biomarkers of allergen immunotherapy

Mateusz Wilk
1
,
Jakub Ptak
1
,
Bartosz Tomczyk
1
,
Adrianna Kruczkowska
1
,
Andrzej Kanturski
1
,
Krzysztof Gomułka
2

  1. Student Research Group of Adult Allergology, Wroclaw Medical University, Wroclaw, Poland Head of the Group: Dr Krzysztof Gomułka
  2. Department of Internal Medicine, Pneumology and Allergology, Wroclaw Medical University, Wroclaw, Poland Head of the Department: Wojciech Barg MD, DSc
Medical Studies/Studia Medyczne 2021; 37 (4): 322–330
Online publish date: 2021/12/31
View full text Get citation
 
PlumX metrics:
Allergen immunotherapy has been shown to be successful in numerous clinical trials, even leading to complete relief of allergic symptoms. However, the molecular mechanisms behind these outcomes remain unclear, substantially hindering introduction of more efficient and safer protocols. The current gold standard of assessing the effects of allergen immunotherapy is a challenge test, which might be both unpleasant and dangerous for patients. Better understanding of the molecular background of allergen immunotherapy would allow us to substitute challenge tests with biomarkers. These might also be used to predict a patient’s response to the treatment. Here, we review current knowledge regarding immune responses to allergen immunotherapy and its potential biomarkers.
keywords:

immunotherapy, allergy, desensitization

Quick links
© 2024 Termedia Sp. z o.o.
Developed by Bentus.