Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer

Piotr Obtulowicz; Marcin Stobiecki; Wojciech Dyga; Tadeusz Popiela; Krystyna Obtulowicz

doi:10.5114/pja.2024.135548

eISSN: 2391-6052
ISSN: 2353-3854

Alergologia Polska - Polish Journal of Allergology

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1/2024
vol. 11

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abstract:

Case report

Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer

Piotr Obtulowicz

¹

,

Marcin Stobiecki

^{2, 3}

,

Wojciech Dyga

^{2, 3}

,

Tadeusz Popiela

^{1, 4}

,

Krystyna Obtulowicz

^{2, 3}

Department of Diagnostic Imaging (NSSU), University Hospital, Krakow, Poland
Department of Clinical and Environmental Allergology, Jagiellonian University Medical College, Krakow, Poland
University Hospital, Hereditary Angioedema Center, Krakow, Poland
Department of Radiology, Jagiellonian University Medical College, Krakow, Poland

Alergologia Polska – Polish Journal of Allergology 2024; 11, 1: 80–83

DOI: https://doi.org/10.5114/pja.2024.135548

Online publish date: 2024/02/20

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AMA

Obtulowicz P, Stobiecki M, Dyga W, Popiela T, Obtulowicz K. Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer. Alergologia Polska - Polish Journal of Allergology. 2024;11(1):80-83. doi:10.5114/pja.2024.135548.

APA

Obtulowicz, P., Stobiecki, M., Dyga, W., Popiela, T.,  & Obtulowicz, K. (2024). Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer. Alergologia Polska - Polish Journal of Allergology, 11(1), 80-83. https://doi.org/10.5114/pja.2024.135548

Chicago

Obtulowicz, Piotr, Marcin Stobiecki, Wojciech Dyga, Tadeusz Popiela,  and Krystyna Obtulowicz. 2024. "Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer". Alergologia Polska - Polish Journal of Allergology 11 (1): 80-83. doi:10.5114/pja.2024.135548.

Harvard

Obtulowicz, P., Stobiecki, M., Dyga, W., Popiela, T.,  and Obtulowicz, K. (2024). Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer. Alergologia Polska - Polish Journal of Allergology, 11(1), pp.80-83. https://doi.org/10.5114/pja.2024.135548

MLA

Obtulowicz, Piotr et al. "Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer." Alergologia Polska - Polish Journal of Allergology, vol. 11, no. 1, 2024, pp. 80-83. doi:10.5114/pja.2024.135548.

Vancouver

Obtulowicz P, Stobiecki M, Dyga W, Popiela T, Obtulowicz K. Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer. Alergologia Polska - Polish Journal of Allergology. 2024;11(1):80-83. doi:10.5114/pja.2024.135548.

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A 30-year-old male with hereditary angioedema (HAE) due to C1 inhibitor deficiency was admitted to the Emergency Department (ED) due to severe abdominal pain lasting for 3 hs with severe bloating and weakness. pdC1INH and fluids were applied as usual and the patient was discharged with feeling better. A few hours later abdominal symptoms recurred and erythema appeared, thus the allergy to antispasmodic drug taken by the patient was suspected. In the ED, the patient received anti-allergic treatment and was discharged again. After 3 h severe abdominal symptoms returned with fever. The patient was readmitted to the ED with peritoneal symptoms. Abdominal X-ray confirmed digestive tract perforation. Laparotomy revealed perforation of the chronic duodenal ulcer. In conclusion, we indicate that a HAE patient with an abdominal pain not resolving after usually effective treatment, should be hospitalized and monitored. Differential diagnosis of reasons other than HAE attack should be made.

keywords:

Abdominal attack in a patient with hereditary angioedema due to C1 inhibitor deficiency complicated by a perforated peptic ulcer

Piotr Obtulowicz 1 , Marcin Stobiecki 2, 3 , Wojciech Dyga 2, 3 , Tadeusz Popiela 1, 4 , Krystyna Obtulowicz 2, 3

abdominal imaging, hereditary angioedema, C1 inhibitor deficiency, angioedema

Piotr Obtulowicz

¹

,

Marcin Stobiecki

^{2, 3}

,

Wojciech Dyga

^{2, 3}

,

Tadeusz Popiela

^{1, 4}

,

Krystyna Obtulowicz

^{2, 3}