Aceclofenac – different from any anti-inflammatory drug directly protecting the joints

Bogusław Okopień

eISSN: 2450-4459
ISSN: 2450-3517

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4/2017
vol. 3

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abstract:

Aceclofenac – different from any anti-inflammatory drug directly protecting the joints

Bogusław Okopień

Online publish date: 2017/09/25

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Aceclofenac belongs to a group of NSAIDs characterised by a strong anti-inflammatory effect. Although it was assumed that it is a prodrug of diclofenac, this is not a completely true statement. Recent pharmacokinetic studies have shown that aceclofenac is slightly metabolised to diclofenac in humans, reaching only a few per cent. The absence of a strong association between diclofenac and aceclofenac is also supported by the results of clinical trials that directly compare these two drugs. Aceclofenac is an effective drug with a good safety profile, especially for side effects from the gastrointestinal tract, compared to diclofenac and non-selective cyclooxygenase inhibitors. In addition, this drug has a protection effect for articular cartilage.

keywords:

Aceclofenac – different from any anti-inflammatory drug directly protecting the joints

Bogusław Okopień

aceclofenac, pain treatment, NSAID, safety of therapy