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eISSN: 2084-9893
ISSN: 0033-2526
Dermatology Review/Przegląd Dermatologiczny
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Open access

without publication fees
2/2024
vol. 111
 
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abstract:
Special paper

Actinic keratosis – diagnostic and therapeutic recommendations of the Polish Dermatological Society

Adam Reich
1
,
Aleksandra Lesiak
2
,
Joanna Narbutt
2
,
Agnieszka Owczarczyk-Saczonek
3
,
Maciej Pastuszczak
4
,
Michał Sobjanek
5
,
Jacek Szepietowski
6
,
Irena Walecka
7, 8
,
Witold Owczarek
9

  1. Department of Dermatology, Institute of Medical Sciences, College of Medical Sciences, University of Rzeszow, Rzeszow, Poland
  2. Department of Dermatology, Paediatric and Oncologic Dermatology, Medical University of Lodz, Lodz, Poland
  3. Department of Dermatology Sexually Transmitted Diseases and Clinical Immunology, University of Warmia and Mazury, Olsztyn, Poland
  4. Clinical Department of Internal Medicine, Dermatology and Allergology in Zabrze, Medical University of Silesia in Katowice, Poland
  5. Department of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland
  6. Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland
  7. Department of Dermatology, National Medical Institute of the Ministry of the Interior and Administration, Warsaw, Poland
  8. Department of Dermatology and Paediatric Dermatology, Centre of Postgraduate Medical Education, Warsaw, Poland
  9. Department of Dermatology, Military Medical Institute, Warsaw, Poland
Dermatol Rev/Przegl Dermatol 2024, 111, 81-96
DOI: https://doi.org/10.5114/dr.2024.142720
Online publish date: 2024/09/13
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Actinic keratosis is a common skin condition that has the potential to develop into malignant neoplastic lesions. Factors that are known to increase the likelihood of developing actinic keratosis include older age, male gender, UV exposure, and immunosuppressive treatment.

Understanding the pathogenesis and significance of actinic keratosis as an initial form of the neoplastic process associated with a sequence of lesions arising on photodamaged skin has led to the concept of field cancerization. The choice of the optimal therapeutic pathway depends on the number of actinic keratosis lesions and the degree of photodamage in the skin, as well as the advancement of skin lesions. The clinical presentation of skin lesions also allows monitoring of the patient’s condition over time and assessing response to treatment, and facilitates rational decisions regarding potential therapy adjustments.

This article outlines the guidelines for the diagnosis and treatment of actinic keratosis in Poland and presents an evidence-based management regimen that incorporates the practical clinical experience of dermatology experts. The recommendations cover a range of topics including topical treatment options, cryosurgery, photodynamic therapy with a photosensitizing agent, and combination treatments.
keywords:

actinic keratosis, treatment, guidelines, recommendations, photodynamic therapy
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