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2/2007
vol. 109 abstract:
Original paper
An analysis of the fundus changes in families with high myopia
Agata Frajdenberg
1
,
Krystyna Pecold
1
,
Monika Podfigurna-Musielak
2
,
Małgorzata Rydzanicz
3
,
Małgorzata Mrugacz
4
,
Suzanne M. Leal
5
,
Bassem A. Bejjani
6
,
Marzena Gajęcka
3, 6
Klinika Oczna 2007, 109 (2): 173-175
Online publish date: 2007/06/12
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Purpose
Of this study is to present fundus changes in members of families with high myopia. Material and methods Detailed clinical examination of the enrolled subjects have been performed in the high myopia families. Both affected (presented with high myopia) and unaffected individuals (without high myopia) are given an ophthalmologic examination: best-corrected visual acuity testing, intraocular pressure examination, fundoscopy, axial length determination (using ultrasonography), refractometry. Results In the 19 high myopia families, 152 individuals were carefully examined. In 11 individuals retinal detachment have been observed. Additionally, myopic degeneration of the central retina (15 cases), degeneration of the peripherical retina (20 subjects), AMD (4 subjects), hypertrophy of the RPE (2 subjects), CNV (1 case), striae medullares (1 case) and macular foramen (1 case), have been identified. Conclusions - In the affected individuals (presented with high myopia) changes of the eye fundus and retinal detachment were more frequently observed comparing to unaffected members of the families without high myopia. - In unaffected individuals genetic factor seems to play insignificant role in apperance of fundus - Changes within central retina in the high myopia individuals may conduce to severe visual impairment. keywords:
high myopia, retinal detachment, peripherical retinal degenerations |
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