eISSN: 1897-4252
ISSN: 1731-5530
Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery
Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Reviewers Abstracting and indexing Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
1/2019
vol. 16
 
Share:
Send email
Share:
abstract:
Original paper

An overlooked fact: thrombocytopenia following bioprosthetic aortic valve replacement

Mehmet Kizilay
1
,
Ferruh Elbir
1
,
Ahmet Arif Aglar
1
,
Unsal Vural
1
,
Ahmet Yavuz Balci
1
,
İbrahim Yekeler
1

  1. Department of Cardiovascular Clinic, Dr Siyami Ersek Hast, Istanbul, Turkey
Kardiochirurgia i Torakochirurgia Polska 2019; 16 (1): 19-26
DOI: https://doi.org/10.5114/kitp.2019.83941
Online publish date: 2019/04/04
View full text Get citation
 
PlumX metrics:
Introduction
Thrombocytopenia observed after bioprosthetic aortic valve replacement has remained a puzzle to solve.

Aim
To analyze thrombocytopenia occurring after bioprosthetic aortic valve replacement by comparison to mechanical aortic valve replacement and coronary artery bypass grafting procedures.

Material and methods
The study was conducted retrospectively on a total of 297 patients who underwent bioprosthetic aortic valve replacement, mechanical prosthetic aortic valve replacement and coronary artery bypass grafting at the cardiovascular surgery department of our clinical center between January 2013 and September 2017. Preoperative and postoperative first 14-day thrombocyte levels of the patients were analyzed.

Results
The postoperative blood thrombocyte level decrease was found to be more significant in patients who underwent bioprosthetic aortic valve replacement than in patients who underwent mechanical aortic valve replacement and coronary artery bypass grafting (p < 0.01). There was also a statistically significant difference in the time to reach the lowest postoperative platelet levels according to type of surgery (p = 0.001; p < 0.01).

Conclusions
When compared to the patients who underwent coronary artery bypass grafting and mechanical prosthetic aortic valve replacement, postoperative thrombocytopenia was found to be more severe in patients who underwent bioprosthetic aortic valve replacement, with a dramatic decrease in thrombocyte count being observed on the postoperative second day. It was found that the thrombocytopenia recovers without causing any problem. We think that the shear forces may play a role in this recovery through washout of chemicals responsible for thrombocytopenia from the glutaraldehyde treated bioprostheses.

keywords:

platelet levels, bleeding complication, bioprosthetic aortic valve replacement
Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2024 Termedia Sp. z o.o.
Developed by Bentus.