Androgen receptor in male breast cancer

Beata Sas-Korczynska; Agnieszka Adamczyk; Joanna Niemiec; Agnieszka Harazin-Lechowska; Aleksandra Ambicka; Jerzy Jakubowicz

doi:10.5114/pjp.2015.57065

eISSN: 2084-9869
ISSN: 1233-9687

Polish Journal of Pathology

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4/2015
vol. 66

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abstract:

Original paper

Androgen receptor in male breast cancer

Beata Sas-Korczynska

,

Agnieszka Adamczyk

,

Joanna Niemiec

,

Agnieszka Harazin-Lechowska

,

Aleksandra Ambicka

,

Jerzy Jakubowicz

Pol J Pathol 2015; 66 (4): 347-352

DOI: https://doi.org/10.5114/pjp.2015.57065

Online publish date: 2016/02/05

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We present the androgen receptor (AR) status in 32 breast cancers diagnosed in male patients. Androgen receptor expression was found in 62.5% tumors and it was more frequent (85% of cases) in estrogen-positive tumours. The analyses of its impact on treatment results showed that AR immmunopositivity is a prognostic factor for overall survival, and AR immunonegativity is also correlated with worse prognosis (distant metastases developed more frequently and earlier).

keywords:

Androgen receptor in male breast cancer

Beata Sas-Korczynska , Agnieszka Adamczyk , Joanna Niemiec , Agnieszka Harazin-Lechowska , Aleksandra Ambicka , Jerzy Jakubowicz

androgen receptor, male breast cancer

Beata Sas-Korczynska

,

Agnieszka Adamczyk

,

Joanna Niemiec

,

Agnieszka Harazin-Lechowska

,

Aleksandra Ambicka

,

Jerzy Jakubowicz