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ISSN: 0031-3939
Pediatria Polska - Polish Journal of Paediatrics
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1/2023
vol. 98
 
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abstract:
Case report

Anti-SARS-CoV-2 antibodies important in diagnostics of acute hepatitis in children

Małgorzata Pawłowska
1, 2
,
Justyna Moppert
1, 2
,
Małgorzata Sobolewska-Pilarczyk
1, 2

  1. Department of Paediatrics, Infectious Diseases and Hepatology, Voivodeship Infectious Observation Hospital, Bydgoszcz, Poland
  2. Department of Infectious Diseases and Hepatology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Torun, Poland
Pediatr Pol 2023; 98 (1): 79-82
DOI: https://doi.org/10.5114/polp.2023.125696
Online publish date: 2023/03/12
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The most common causes of acute hepatitis in children are hepatitis A and autoimmune hepatitis. Hepatitis in the course of Wilson’s disease is sporadically registered in adolescents.

An increase of activity of aminotransferases both in the course of multisystem inflammatory syndrome in children (MIS-C) and in the course of COVID-19 has been observed. Hepatitis is common in children with MIS-C and is associated with a more severe presentation and persistent elevation of liver function tests.

To date, no cases of acute hepatitis in children due to COVID-19 have been reported.

We present 2 cases of acute hepatitis in children where the only cause seems to be a previous asymptomatic SARS-CoV-2 infection.
keywords:

hepatitis, SARS-CoV-2 infection, anti-SARS-CoV-2 antibodies, MIS-C