Anticancer properties of polysaccharides isolated from fungi of the Basidiomycetes class

Marta Lemieszek; Wojciech Rzeski

doi:10.5114/wo.2012.30055

eISSN: 1897-4309
ISSN: 1428-2526

Contemporary Oncology/Współczesna Onkologia

Current issue Archive Manuscripts accepted About the journal Supplements Addendum Special Issues Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

4/2012
vol. 16

Send email

Copy url:

abstract:

Review paper

Anticancer properties of polysaccharides isolated from fungi of the Basidiomycetes class

Marta Lemieszek

,

Wojciech Rzeski

Wspolczesna Onkol 2012; 16 (4): 285–289

DOI: https://doi.org/10.5114/wo.2012.30055

Online publish date: 2012/09/29

View full text Get citation

PlumX metrics:

Basidiomycete mushrooms represent a valuable source of biologically active compounds with anticancer properties. This feature is primarily attributed to polysaccharides and their derivatives. The anticancer potential of polysaccharides is linked to their origin, composition and chemical structure, solubility and method of isolation. Moreover, their activity can be significantly increased by chemical modifications. Anticancer effects of polysaccharides can be expressed indirectly (immunostimulation) or directly (cell proliferation inhibition and/or apopto-sis induction). Among the wide range of polysaccharides with documented anticancer properties, lentinan, polysaccharide-K (PSK) and schizophyllan deserve special attention. These polysaccharides for many years have been successfully applied in cancer treatment and their mechanism of action is the best known.

keywords:

Anticancer properties of polysaccharides isolated from fungi of the Basidiomycetes class

Marta Lemieszek , Wojciech Rzeski

Basidiomycetes, anticancer properties, polysaccharides, lentinan, PSK, Krestin, schizophyllan

Marta Lemieszek

,

Wojciech Rzeski