Antiplatelets in acute coronary syndrome in Poland – from guidelines to clinical practice

Stanisław Tubek; Wiktor Kuliczkowski; Mariusz Gąsior; Marek Gierlotka; Jacek Kubica; Andrzej Budaj; Adam Witkowski; Krzysztof Reczuch; Piotr Ponikowski

doi:10.5114/aic.2021.107492

eISSN: 1897-4295
ISSN: 1734-9338

Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej

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abstract:

Review paper

Antiplatelets in acute coronary syndrome in Poland – from guidelines to clinical practice

Stanisław Tubek

¹

,

Wiktor Kuliczkowski

²

,

Mariusz Gąsior

³

,

Marek Gierlotka

⁴

,

Jacek Kubica

⁵

,

Andrzej Budaj

⁶

,

Adam Witkowski

⁷

,

Krzysztof Reczuch

¹

,

Piotr Ponikowski

¹

Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland
Department of Cardiology, Wroclaw Medical University, Wroclaw, Poland
3rd Department of Cardiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland
Department of Cardiology, Institute of Medical Sciences, University of Opole, Opole, Poland
Department of Cardiology and Internal Medicine, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland
Department of Cardiology, Centre of Postgraduate Medical Education, Grochowski Hospital, Warsaw, Poland
Department of Interventional Cardiology and Angiology, National Institute of Cardiology, Warsaw, Poland

Adv Interv Cardiol 2021; 17, 2 (64): 141–154

DOI: https://doi.org/10.5114/aic.2021.107492

Online publish date: 2021/07/09

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AMA

Tubek S, Kuliczkowski W, Gąsior M, et al. Antiplatelets in acute coronary syndrome in Poland – from guidelines to clinical practice. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2021;17(2):141-154. doi:10.5114/aic.2021.107492.

APA

Tubek, S., Kuliczkowski, W., Gąsior, M., Gierlotka, M., Kubica, J.,  & Budaj, A. et al. (2021). Antiplatelets in acute coronary syndrome in Poland – from guidelines to clinical practice. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, 17(2), 141-154. https://doi.org/10.5114/aic.2021.107492

Chicago

Tubek, Stanisław, Wiktor Kuliczkowski, Mariusz Gąsior, Marek Gierlotka, Jacek Kubica, Andrzej Budaj,  and Adam Witkowski et al. 2021. "Antiplatelets in acute coronary syndrome in Poland – from guidelines to clinical practice". Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej 17 (2): 141-154. doi:10.5114/aic.2021.107492.

Harvard

Tubek, S., Kuliczkowski, W., Gąsior, M., Gierlotka, M., Kubica, J., Budaj, A., Witkowski, A., Reczuch, K.,  and Ponikowski, P. (2021). Antiplatelets in acute coronary syndrome in Poland – from guidelines to clinical practice. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, 17(2), pp.141-154. https://doi.org/10.5114/aic.2021.107492

MLA

Tubek, Stanisław et al. "Antiplatelets in acute coronary syndrome in Poland – from guidelines to clinical practice." Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, vol. 17, no. 2, 2021, pp. 141-154. doi:10.5114/aic.2021.107492.

Vancouver

Tubek S, Kuliczkowski W, Gąsior M, Gierlotka M, Kubica J, Budaj A et al. Antiplatelets in acute coronary syndrome in Poland – from guidelines to clinical practice. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2021;17(2):141-154. doi:10.5114/aic.2021.107492.

Acute coronary syndrome is a factor for poor prognosis and recurrent cardiovascular events. Adequate antiplatelet therapy is crucial in patients with the acute coronary syndrome for risk reduction. Such treatment is well described in four documents issued by the European Society of Cardiology, which precisely illustrate the use of antiplatelets in the settings of ST-elevated and non-ST elevated myocardial infarction. Despite its unquestioned role in the treatment of acute coronary syndrome, recent real-world-data from Polish registries reveal poor adherence to the guidelines-recommended antiplatelet treatment in Poland. Thus, we present here a comprehensive review of the use of antiplatelets in the settings of the acute coronary syndrome. Each phase of the treatment, i.e. pre-hospital, in-hospital and post-hospital, is discussed separately for a better understanding of the decision-making process at each step. We also present unpublished data from Polish registries (e.g. PL-ACS 2019, National Registry of Procedures of Invasive Cardiology, RECEPTOmetrPEX panel) regarding adherence to the guidelines-recommended treatment in Poland, thus highlighting the points of care which should be immediately improved. It has to be stressed here that careful assessment of ischaemic and bleeding risk has to be performed in each patient with acute coronary syndrome individually and repeated at successive phases of the treatment. Only such an approach allows for appropriate antiplatelet therapy tailoring.

keywords:

Antiplatelets in acute coronary syndrome in Poland – from guidelines to clinical practice

Stanisław Tubek 1 , Wiktor Kuliczkowski 2 , Mariusz Gąsior 3 , Marek Gierlotka 4 , Jacek Kubica 5 , Andrzej Budaj 6 , Adam Witkowski 7 , Krzysztof Reczuch 1 , Piotr Ponikowski 1

guidelines, antiplatelet treatment, ST elevation myocardial infarction, non-ST elevation myocardial infarction

Stanisław Tubek

¹

,

Wiktor Kuliczkowski

²

,

Mariusz Gąsior

³

,

Marek Gierlotka

⁴

,

Jacek Kubica

⁵

,

Andrzej Budaj

⁶

,

Adam Witkowski

⁷

,

Krzysztof Reczuch

¹

,

Piotr Ponikowski

¹