eISSN: 1897-4295
ISSN: 1734-9338
Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej
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1/2008
vol. 4
 
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abstract:

Original article
Should perimembranous ventricular septal defects still be treated percutaneously?

Małgorzata Pawelec-Wojtalik
,
Waldemar Bobkowski
,
Bartłomiej Mroziński
,
Rafał Surmacz
,
Wojciech Mrówczyński
,
Andrzej Wodziński
,
Alicja Bartkowska-Śniatkowska
,
Rafał Bartkowski
,
Arkadiusz Biniaś

Post Kardiol Interw 2008; 4, 1 (11): 1–9
Online publish date: 2008/04/10
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Aim: Assessment of perimembraneous ventricular septal defects (VSD) treatment with the use of AMembrVSDO and evaluation of the early and late complication risk. Methods: In the period from June, 2003 to August, 2005, 17 patients were qualified for VSD transcatheter closure. Patients aged 1.2-18.0 years (mean 9.2±6.5), weighted 9.4-72.0 kg (mean 32.9±21.8). The follow-up period was 3-4 years.
Results: The procedure was performed successfully in 15 out of 17 children. The left ventricle end-diastolic dimension decreased statistically after the procedure (p=0.00005). One child (6.7%) suffered from a complete atrioventricular block after the VSD closure. Minor complications were observed in 4 (26.7%) cases. Statistically significant differences were observed between the size of the device and the short diameter of the VSD (p=0.7600), the long diameter of the VSD (p=0.8152), the angiographic diameter of the VSD (p=0.9210) as well as the proposed device (p=0.9202). After VSD closure, the number of patients with TI >I° decreased from 66.7% to 6.7% (p=0.0159) and, in case of those with MI, from 93.3% to 60% (p=0.0270).
Conclusion: Percutaneous closure of the perimembranous VSD with AMembrVSDO is a promising method of treatment. Nevertheless, more frequent occurrence of the complete heart block following the above-mentioned procedure in comparison to surgery indicates that the qualification for AMembrVSDO implantation should be performed very carefully. More data is needed to verify safety of this procedure.
keywords:

perimembranous ventricular septal defect, Amplatzer, transcatheter occlusion

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