eISSN: 1897-4295
ISSN: 1734-9338
Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej
Current issue Archive Manuscripts accepted About the journal Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
Editorial Policies
Sarajevo Declaration on Integrity and Visibility of Scholarly Publications
1/2010
vol. 6
 
Share:
Send email
Share:
abstract:

Original paper
Dual-source computed tomography angiography in patients after bypass grafting – comparison with invasive coronary angiography

Cezary Kępka
,
Maksymilian P. Opolski
,
Mariusz Kruk
,
Jerzy Pręgowski
,
Ilona Michałowska
,
Marcin Demkow
,
Adam Witkowski
,
Witold Rużyłło

Post Kardiol Interw 2010; 6, 1 (19): 12-20
DOI: https://doi.org/10.5114/pwki.2010.13821
Online publish date: 2010/04/12
View full text Get citation
 
Background: Assessment of bypass grafts by invasive coronary angiography (ICA) is bothersome and often requires extra procedure time, contrast load, and radiation exposure.
Aim: To evaluate the ability of dual-source computed tomography angiography (CTA) to detect significant graft disease in symptomatic patients after coronary artery bypass grafting (CABG).
Methods: Thirty (26 men, mean age 66 ± 9 years) consecutive post-CABG patients from the prospective ANIN Computed Tomography Angiography Registry who underwent both dual-source CTA and ICA for suspected graft disease were included in the analysis. Coronary artery bypass grafts, anastomotic sites, and distal runoffs with a diameter of ≥ 1.5 mm were evaluated for the presence of significant stenoses (≥ 50% diameter reduction). Invasive coronary angiography served as a reference standard, and was performed within ≤ 30 days of dual-source CTA.
Results: A total of 58 bypass grafts with 56 anastomotic sites, and 54 distal runoffs were evaluable both in dual-source CTA and ICA. Sensitivity, specificity, and positive and negative predictive values of dual-source CTA for the detection of significant lesions in bypass grafts were 100%, 92%, 86%, and 100%, respectively. In anastomotic sites, dual-source CTA detected significant stenosis with a sensitivity and specificity of 100% and 96%, respectively. If analysis was restricted to distal runoff segments, sensitivity and specificity were 50% and 98%, respectively. On a per-patient basis, all patients with at least one significant graft stenosis on ICA were correctly classified using dual-source CTA.
Conclusions: Dual-source CTA permits the reliable assessment of bypass graft disease with high diagnostic accuracy and can be used in clinical routine as a noninvasive test to rule out suspected graft dysfunction in symptomatic post-CABG patients.
keywords:

dual-source computed tomography angiography, coronary artery bypass grafts, anastomotic sites, distal runoff segments
Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2024 Termedia Sp. z o.o.
Developed by Bentus.