eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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3/2006
vol. 23
 
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abstract:

Original paper
Lichen myxedematosus – diagnostic difficulties. A case report

Dorota Jenerowicz
,
Agnieszka Ziembicka
,
Karolina Piotrowska
,
Anna Neneman

Post Dermatol Alergol 2006; XXIII, 3: 138–142
Online publish date: 2006/06/23
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Lichen myxedematosus (papular mucinosis) comprises the group of conditions associated with deposition of mucin in the skin. Because of considerable variability and complexity of its forms, this rare dermatosis may often cause diagnostic difficulties. New and updated classification of lichen myxedematosus by Rongioletti and Rebora [1] includes 3 variants of the disease: generalized (scleromyxedema), localized and atypical. Lichen myxedematosus is often recognized as a chronic benign condition, however, in its generalized form it may be associated with monoclonal gammopathy (mostly types IgG λ and κ) and its course may be unfavorable for the patient. In the case of lichen myxedematosus both choice and efficacy of the treatment depend significantly on disease variant and the majority of literature reports refer to the treatment with glucocorticosteroids, cytostatic agents, interferon α, plasmapheresis, photoferesis, radiation therapy and PUVA-therapy (including PUVA-bath).
keywords:

lichen myxedematosus, mucinosis, photochemotherapy
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