eISSN: 1897-4309
ISSN: 1428-2526
Contemporary Oncology/Współczesna Onkologia
Current issue Archive Manuscripts accepted About the journal Supplements Addendum Special Issues Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
6/1999
vol. 3
 
Share:
Share:
abstract:

Aspects of use of selected metal complexes in anti-cancer therapy

Tomasz Dąbrowski

Współcz Onkol (1999) 6, 249-252
Online publish date: 2003/08/07
View full text Get citation
 
The anti-cancer properties and clinical usefulness of cisplatin and its derivatives indicated a need of searching for other metal complexes of similar activities. Anti-cancer activity was proved for complexes of titanium (IV), germanium (IV), gallium (III), ruthenium (III), palladium (II) and tin (IV). Only the first three of them favourably passed I/II phase of clinical trials.

In this article the actual state of knowledge about mechanisms of activity of several titanium, germanium and gallium complexes, profiles of their anti-cancer activity observed in in vivo and in vitro laboratory investigations as well as conducted clinical trials are presented.
keywords:

ati-cancer metal complexes, cytotoxicity

Quick links
© 2024 Termedia Sp. z o.o.
Developed by Bentus.