Assessment of mitral regurgitation and mitral complex geometry in patients after transcatheter aortic valve implantation

Danuta Sorysz; Agata Krawczyk-Ożóg; Artur Dziewierz; Tomasz Tokarek; Barbara Zawiślak; Mateusz Hołda; Kinga Komnata; Andrzej Surdacki; Stanisław Bartuś; Dariusz Dudek

doi:10.5114/aic.2020.99265

eISSN: 1897-4295
ISSN: 1734-9338

Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej

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abstract:

Original paper

Assessment of mitral regurgitation and mitral complex geometry in patients after transcatheter aortic valve implantation

Danuta Sorysz

¹

,

Agata Krawczyk-Ożóg

¹

,

Artur Dziewierz

^{1, 2}

,

Tomasz Tokarek

¹

,

Barbara Zawiślak

¹

,

Mateusz Hołda

^{3, 4}

,

Kinga Komnata

⁵

,

Andrzej Surdacki

^{1, 2}

,

Stanisław Bartuś

^{1, 2}

,

Dariusz Dudek

^{1, 2}

Department of Cardiology and Cardiovascular Interventions, University Hospital, Krakow, Poland
Second Department of Cardiology, Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland
HEART – Heart Embryology and Anatomy Research Team, Department of Anatomy, Jagiellonian University Medical College, Krakow, Poland
Division of Cardiovascular Sciences, The University of Manchester, Manchester, UK
Research Student, Jagiellonian University Medical College, Krakow, Poland

Adv Interv Cardiol 2020; 16, 3 (61): 300–305

DOI: https://doi.org/10.5114/aic.2020.99265

Online publish date: 2020/10/02

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AMA

Sorysz D, Krawczyk-Ożóg A, Dziewierz A, et al. Assessment of mitral regurgitation and mitral complex geometry in patients after transcatheter aortic valve implantation. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2020;16(3):300-305. doi:10.5114/aic.2020.99265.

APA

Sorysz, D., Krawczyk-Ożóg, A., Dziewierz, A., Tokarek, T., Zawiślak, B.,  & Hołda, M. et al. (2020). Assessment of mitral regurgitation and mitral complex geometry in patients after transcatheter aortic valve implantation. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, 16(3), 300-305. https://doi.org/10.5114/aic.2020.99265

Chicago

Sorysz, Danuta, Agata Krawczyk-Ożóg, Artur Dziewierz, Tomasz Tokarek, Barbara Zawiślak, Mateusz Hołda,  and Kinga Komnata et al. 2020. "Assessment of mitral regurgitation and mitral complex geometry in patients after transcatheter aortic valve implantation". Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej 16 (3): 300-305. doi:10.5114/aic.2020.99265.

Harvard

Sorysz, D., Krawczyk-Ożóg, A., Dziewierz, A., Tokarek, T., Zawiślak, B., Hołda, M., Komnata, K., Surdacki, A., Bartuś, S.,  and Dudek, D. (2020). Assessment of mitral regurgitation and mitral complex geometry in patients after transcatheter aortic valve implantation. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, 16(3), pp.300-305. https://doi.org/10.5114/aic.2020.99265

MLA

Sorysz, Danuta et al. "Assessment of mitral regurgitation and mitral complex geometry in patients after transcatheter aortic valve implantation." Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, vol. 16, no. 3, 2020, pp. 300-305. doi:10.5114/aic.2020.99265.

Vancouver

Sorysz D, Krawczyk-Ożóg A, Dziewierz A, Tokarek T, Zawiślak B, Hołda M et al. Assessment of mitral regurgitation and mitral complex geometry in patients after transcatheter aortic valve implantation. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2020;16(3):300-305. doi:10.5114/aic.2020.99265.

Introduction
Mitral regurgitation (MR) of varying degrees and mechanisms is a common finding in patients with aortic stenosis with different improvement after transcatheter aortic valve implantation (TAVI).

Aim
To evaluate the impact of TAVI on mitral complex geometry and the degree of MR.

Material and methods
A total of 31 patients (29.0% males) with severe aortic stenosis and moderate or severe MR at the baseline who underwent TAVI were included in this study. Clinical and echocardiographic characteristics were determined at baseline and at 6 and 12 months.

Results
After TAVI, decrease of MR vena contracta width (p = 0.00002, p = 0.00004), aorto-mural mitral annulus diameter (p = 0.00008, p = 0.02), increase of mitral annular plane systolic excursion (p = 0.0004, p = 0.0003), left ventricular stroke volume (p = 0.0003, p = 0.0004), ejection fraction (p = 0.0004, p = 0.01) and decrease of major dimension of left ventricle in three chamber view (p = 0.05, p = 0.002) were observed in patients at both time points. Additionally, we observed a decrease of distance between the head of the papillary muscles (p = 0.003) at 6 months and a decrease of left atrium volume index (p = 0.01) and systolic pulmonary artery pressure (p = 0.01) at 12 months.

Conclusions
Patients with moderate or severe MR undergoing TAVI achieved significant improvement of mitral valve complex function resulting in the reduction of MR degree.

keywords:

Assessment of mitral regurgitation and mitral complex geometry in patients after transcatheter aortic valve implantation

Danuta Sorysz 1 , Agata Krawczyk-Ożóg 1 , Artur Dziewierz 1, 2 , Tomasz Tokarek 1 , Barbara Zawiślak 1 , Mateusz Hołda 3, 4 , Kinga Komnata 5 , Andrzej Surdacki 1, 2 , Stanisław Bartuś 1, 2 , Dariusz Dudek 1, 2

transcatheter aortic valve implantation, mitral regurgitation, mitral valve complex, aortic stenosis

Danuta Sorysz

¹

,

Agata Krawczyk-Ożóg

¹

,

Artur Dziewierz

^{1, 2}

,

Tomasz Tokarek

¹

,

Barbara Zawiślak

¹

,

Mateusz Hołda

^{3, 4}

,

Kinga Komnata

⁵

,

Andrzej Surdacki

^{1, 2}

,

Stanisław Bartuś

^{1, 2}

,

Dariusz Dudek

^{1, 2}