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eISSN: 2719-3209
ISSN: 0023-2157
Klinika Oczna / Acta Ophthalmologica Polonica
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4/2007
vol. 109
 
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abstract:
Original paper

Assessment of sFas concentration in serum of uveitis patients

Małgorzata Mrugacz
1
,
Alina Bakunowicz-Łazarczyk
1
,
Dorota Średzińska-Kita
1
,
Beata Żelazowska-Rutkowska
2
,
Jolanta Wysocka
2

  1. Z Kliniki Okulistyki Dziecięcej Akademii Medycznej w Białymstoku
  2. Z Zakładu Pediatrycznej Diagnostyki Laboratoryjnej Akademii Medycznej w Białymstoku
Klinika Oczna 2007, 109 (4): 432-434
Online publish date: 2007/12/20
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Purpose
To evaluate the concentration of sFas in serum of uveitis patients.

Material and methods
Serum samples were collected from 13 patients with uveitis and 12 controls. All patients have underwent ophthalmic and laboratory examinations. The sFas levels were determined by immunoenzymatic

Results
We found statistically increased levels of sFas in serum of patients with uveitis compared with controls.

Conclusions
Our results suggest a systemic nature of uveitis with persistent activation of the immune system. Apoptosis may play regulatory role in ocular inflammation of patients with uveitis.

keywords:

cytokines, Sjögren’s syndrome, tear fluid

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