Atherosclerosis: risk assessment and the role of aiming for optimal glycaemic control in young patients with type 1 diabetes

Martyna Kolasa; Aleksandra Olejnik; Ewa Rusak; Agata Chobot

doi:10.5114/pedm.2022.122546

eISSN: 2083-8441
ISSN: 2081-237X

Pediatric Endocrinology Diabetes and Metabolism

Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

Journal integrated with

1/2023
vol. 29

Send email

Copy url:

abstract:

Review paper

Atherosclerosis: risk assessment and the role of aiming for optimal glycaemic control in young patients with type 1 diabetes

Martyna Kolasa

¹

,

Aleksandra Olejnik

¹

,

Ewa Rusak

²

,

Agata Chobot

³

University Clinical Hospital in Opole, Poland
Department of Children’s Diabetology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland
Department of Pediatrics, Institute of Medical Sciences, University of Opole, Poland

Pediatr Endocrinol Diabetes Metab 2023; 29 (1): 42-47

DOI: https://doi.org/10.5114/pedm.2022.122546

Online publish date: 2022/12/17

View full text Get citation

PlumX metrics:

Compared with healthy children, peers with type 1 diabetes mellitus (DM1) have an increased risk of developing advanced atherosclerosis and cardiovascular disease (CVD). Glycaemic control is the most important modifiable risk factor for CVD in DM1. Currently, monitoring of glycaemic control relies on glycosylated haemoglobin levels (HbA1c), self-monitoring of blood glucose (SMBG), and the use of continuous glucose monitoring (CGM) systems. The flow-mediated dilatation (FMD), pulse wave velocity (PWV), ankle-brachial index (ABI), and carotid intima-media thickness (cIMT) may be used to assess the risk of CVD, by estimating the process of atherosclerosis in peripheral vessels.

Aim of the study: To summarize the current literature on the correlation of metabolic control in young people with DM1, assessed by key metrics from CGM reports, and the development of atherosclerosis and the incidence of CVD.

Conclusions: Chronic hyperglycaemia is an independent risk factor for vascular changes. The effect of glycaemic control – assessed on the basis of parameters obtained from CGM reports – on the risk of CVD in DM1 has been analysed in few studies, especially in the paediatric population.

keywords:

Atherosclerosis: risk assessment and the role of aiming for optimal glycaemic control in young patients with type 1 diabetes

Martyna Kolasa 1 , Aleksandra Olejnik 1 , Ewa Rusak 2 , Agata Chobot 3

type 1 diabetes mellitus, atherosclerosis, CGM, CVD, IMT

Martyna Kolasa

¹

,

Aleksandra Olejnik

¹

,

Ewa Rusak

²

,

Agata Chobot

³