Atypical bilateral cerebellopontine angle medulloblastoma: differential diagnosis, immunohistochemical features and radiological presentation

Kelvin M. Pińa Batista; Sayoa Alvarez de Eulate-Beramendi; María Rico; Victor Rodrigo; Yordy E. Batista Batista; Kenia Y. Alvarez Reyes

doi:10.5114/wo.2017.69593

eISSN: 1897-4309
ISSN: 1428-2526

Contemporary Oncology/Współczesna Onkologia

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3/2017
vol. 21

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abstract:

Case report

Atypical bilateral cerebellopontine angle medulloblastoma: differential diagnosis, immunohistochemical features and radiological presentation

Kelvin M. Pińa Batista

,

Sayoa Alvarez de Eulate-Beramendi

,

María Rico

,

Victor Rodrigo

,

Yordy E. Batista Batista

,

Kenia Y. Alvarez Reyes

Contemp Oncol (Pozn) 2017; 21 (3): 249–253

DOI: https://doi.org/10.5114/wo.2017.69593

Online publish date: 2017/09/29

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AMA

Batista K, Eulate-Beramendi S, Rico M, Rodrigo V, Batista Y, Reyes K. Atypical bilateral cerebellopontine angle medulloblastoma: differential diagnosis, immunohistochemical features and radiological presentation. Contemporary Oncology/Współczesna Onkologia. 2017;21(3):249-253. doi:10.5114/wo.2017.69593.

APA

Batista, K., Eulate-Beramendi, S., Rico, M., Rodrigo, V., Batista, Y.,  & Reyes, K. (2017). Atypical bilateral cerebellopontine angle medulloblastoma: differential diagnosis, immunohistochemical features and radiological presentation. Contemporary Oncology/Współczesna Onkologia, 21(3), 249-253. https://doi.org/10.5114/wo.2017.69593

Chicago

Batista, Kelvin M. Pińa, Sayoa Alvarez de Eulate-Beramendi, María Rico, Victor Rodrigo, Yordy E. Batista Batista,  and Kenia Y. Alvarez Reyes. 2017. "Atypical bilateral cerebellopontine angle medulloblastoma: differential diagnosis, immunohistochemical features and radiological presentation". Contemporary Oncology/Współczesna Onkologia 21 (3): 249-253. doi:10.5114/wo.2017.69593.

Harvard

Batista, K., Eulate-Beramendi, S., Rico, M., Rodrigo, V., Batista, Y.,  and Reyes, K. (2017). Atypical bilateral cerebellopontine angle medulloblastoma: differential diagnosis, immunohistochemical features and radiological presentation. Contemporary Oncology/Współczesna Onkologia, 21(3), pp.249-253. https://doi.org/10.5114/wo.2017.69593

MLA

Batista, Kelvin M. Pińa et al. "Atypical bilateral cerebellopontine angle medulloblastoma: differential diagnosis, immunohistochemical features and radiological presentation." Contemporary Oncology/Współczesna Onkologia, vol. 21, no. 3, 2017, pp. 249-253. doi:10.5114/wo.2017.69593.

Vancouver

Batista K, Eulate-Beramendi S, Rico M, Rodrigo V, Batista Y, Reyes K. Atypical bilateral cerebellopontine angle medulloblastoma: differential diagnosis, immunohistochemical features and radiological presentation. Contemporary Oncology/Współczesna Onkologia. 2017;21(3):249-253. doi:10.5114/wo.2017.69593.

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Medulloblastoma (MB) is a highly aggressive soft tissue neoplasm, classified as a primitive neuroectodermal tumor. It is the most common posterior fossa tumor in children, but occurs rarely in adults. MB accounts for approximately 20% of all primary central nervous system (CNS) tumors of childhood, while its incidence is around 1% of adult brain tumors. Most often it occurs in the cerebellum. We report a case of multicentric MB involving the bilateral cerebellopontine angle (CPA) and right cerebellar hemisphere. The tumor showed isointensity on T1/T2-weighted images, and slight hyperintensity on T2-weighted fluid-attenuated inversion-recovery (FLAIR) images. The MB had restricted diffusion on diffusion-weighted images (DWI). It was not easy to make an accurate diagnosis before biopsy. The lesion in our patient presented with atypical MR image features of medulloblastoma. To our knowledge, this is the first case of bilateral CPA MB.

keywords:

Atypical bilateral cerebellopontine angle medulloblastoma: differential diagnosis, immunohistochemical features and radiological presentation

Kelvin M. Pińa Batista , Sayoa Alvarez de Eulate-Beramendi , María Rico , Victor Rodrigo , Yordy E. Batista Batista , Kenia Y. Alvarez Reyes

medulloblastoma; bilateral; cerebellopontine angle

Kelvin M. Pińa Batista

,

Sayoa Alvarez de Eulate-Beramendi

,

María Rico

,

Victor Rodrigo

,

Yordy E. Batista Batista

,

Kenia Y. Alvarez Reyes