en POLSKI
eISSN: 2300-8660
ISSN: 0031-3939
Pediatria Polska - Polish Journal of Paediatrics
Current issue Archive Manuscripts accepted About the journal Editorial board Abstracting and indexing Contact Instructions for authors Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
Editorial Policies
Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

1/2024
vol. 99
 
Share:
Send email
Share:
abstract:
Case report

Autoimmune polyglandular syndrome type 2 in the form of Carpenter syndrome in a 16.5-year-old girl

Hanna Nowak
1
,
Dominika Maria Szwacka
1
,
Marek Niedziela
2
,
Witold Stankiewicz
3
,
Monika Obara-Moszyńska
2

  1. Student Scientific Society of Paediatric Endocrinology, Poznań University of Medical Sciences, Poznań, Poland
  2. Department of Paediatric Endocrinology and Rheumatology, Institute of Paediatrics, Poznań University of Medical Sciences, Poznań, Poland
  3. Department of Paediatric Diabetes, Clinical Auxology and Obesity, Institute of Paediatrics, Poznań University of Medical Sciences, Poznań, Poland
Pediatr Pol 2024; 99 (1):84 -88
DOI: https://doi.org/10.5114/polp.2024.135701
Online publish date: 2024/02/26
View full text Get citation
 
PlumX metrics:
Autoimmune polyglandular syndrome type 2 (APS-2) is the coexistence of Addison disease and at least one of the disorders like autoimmune thyroid diseases and/or type 1 diabetes mellitus. We discuss the case of 16.5-year-old girl who had been diagnosed with APS-2 at the early age of 13.5 years. The girl presented recurrent abdominal pain and emesis for about 3 years, occurring about every 6 months. Moreover, in physical examination, characteristic skin hyperpigmentation furrows in the hands, nipples, and mucosa in the oral cavity were noticed. Due to the clinical picture and laboratory data, autoimmune thyroiditis and primary adrenal insufficiency were diagnosed. After initiating substitution treatment, the girl developed full-blown diabetes mellitus, probably masked earlier after primary adrenal insufficiency. It should be kept in mind that during the diagnosis of autoimmune disease, other autoimmune disorders may coexist; thus, such patients should be under specialists’ close supervision.
keywords:

Carpenter syndrome, autoimmune polyglandular syndrome, girl