Autologous fat grafting in the treatment of hard-to-heal wounds
of lower extremities: surgical technique and examples

Alina Hedrych-Ozimina; Adrian Różycki; Karolina Kondej; Agnieszka Brzezicka; Jerzy Jankau

doi:10.5114/dr.2024.142133

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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2/2024
vol. 111

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abstract:

Case report

Autologous fat grafting in the treatment of hard-to-heal wounds of lower extremities: surgical technique and examples

Alina Hedrych-Ozimina

¹

,

Adrian Różycki

¹

,

Karolina Kondej

¹

,

Agnieszka Brzezicka

¹

,

Jerzy Jankau

¹

Division of Plastic Surgery, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland

Dermatol Rev/Przegl Dermatol 2024, 111, 132-139

DOI: https://doi.org/10.5114/dr.2024.142133

Online publish date: 2024/09/13

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Introduction:
Management of hard-to-heal wounds of lower extremities includes casual and local treatment. Autologous fat grafting performed within such wound is one of therapeutic approaches in this disorder. Adipose-derived stem cells present in fat may play a key role in wound healing promotion due to their proangiogenic and regenerative properties.

Objective:
In this article we have described the surgical technique of autologous fat grafting and reported cases of patients suffering from chronic wounds of various etiologies, who had undergone autologous fat grafting because of the failure of standard management.

Case report:
Significant progress in wound healing was observed in 4 cases, in 1 case the wound closed completely, however in 1 patient the effect was unsatisfactory. No adverse effects of autologous fat grafting were observed.

Conclusions:
In order to take full advantage of autologous fat’s potential, standardization of the surgical technique providing the greatest improvement in healing depending on the ulcer size and etiology is needed.

keywords:

Autologous fat grafting in the treatment of hard-to-heal wounds of lower extremities: surgical technique and examples

Alina Hedrych-Ozimina 1 , Adrian Różycki 1 , Karolina Kondej 1 , Agnieszka Brzezicka 1 , Jerzy Jankau 1

wound healing, adipose tissue, leg ulcer, adipose-derived mesenchymal stem cells

Alina Hedrych-Ozimina

¹

,

Adrian Różycki

¹

,

Karolina Kondej

¹

,

Agnieszka Brzezicka

¹

,

Jerzy Jankau

¹