Azelaic acid in dermatological treatment – current state of knowledge

Radomir Reszke; Jacek Szepietowski

doi:10.5114/dr.2016.61785

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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4/2016
vol. 103

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abstract:

Review paper

Azelaic acid in dermatological treatment – current state of knowledge

Radomir Reszke

,

Jacek Szepietowski

Przegl Dermatol 2016, 103, 337–343

DOI: https://doi.org/10.5114/dr.2016.61785

Online publish date: 2016/09/01

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Azelaic acid (AZA) is a naturally occurring substance produced by Malassezia furfur which exerts various effects on the skin. Azelaic acid has antibacterial, anti-inflammatory, keratolytic, comedolytic, sebostatic and tyrosinase-inhibiting properties. Topical application of AZA as 20% cream or 15% gel is a well-established therapeutic method in various common dermatoses, mainly acne vulgaris, rosacea and disorders associated with hyperpigmentation. Azelaic acid is used as a component of chemical peels as well. The paper summarizes the most relevant issues concerning AZA application in dermatological treatment based on current knowledge.

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Azelaic acid in dermatological treatment – current state of knowledge

Radomir Reszke , Jacek Szepietowski

azelaic acid, topical treatment, dermatoses

Radomir Reszke

,

Jacek Szepietowski