eISSN: 1897-4252
ISSN: 1731-5530
Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery
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1/2007
vol. 4
 
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abstract:

Badania Kliniczne i Doświadczalne w Chorobach Serca, Płuc i Naczyń
Immunosuppression protocols in lung transplantation taking into account own experience

Jacek Wojarski
,
Ewa Kucewicz-Czech
,
Roman Przybylski
,
Dariusz Jastrzębski
,
Michał Zakliczyński
,
Marian Zembala

Kardiochirurgia i Torakochirurgia Polska 2007; 4 (1): 66–70
Online publish date: 2007/04/05
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Acute cellular rejection in lung transplantation (LTx) is extremely strong. Long-term results of LTx are limited by bronchiolitis obliterans, which is a process associated by many authors with „chronic rejection” [1]. This may lead to the conclusion that improvement of immunosuppression will limit the occurrence and severity of OB. The optimal immunosuppressive regimen still remains to be established – especially when new drugs become available. The authors describe immunosuppressive drugs that may be currently used for LTx patients. Medical aspects directing decisions about a model of immunosuppression are also described. Own clinical experience with a novel immunosuppressive regimen is discussed.
keywords:

lung transplantation, immunosuppression rejection, complications
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