Biological drugs in the treatment of atopic dermatitis – recommendations of the Polish Dermatological Society, 
the Polish Society of Allergology, the Polish Pediatric Society 
and the Polish Society of Family Medicine

Roman Nowicki; Magdalena Trzeciak; Lidia Rudnicka; Jacek Szepietowski; Marek Kulus; Maciej Kupczyk; Agnieszka Mastalerz-Migas; Jarosław Peregud-Pogorzelski; Karina Jahnz-Różyk; Joanna Narbutt; Magdalena Czarnecka-Operacz; Rafal Czajkowski; Elżbieta Grubska-Suchanek; Dorota Krasowska; Beata Kręcisz; Cezary Kowalewski; Aleksandra Lesiak; Malgorzata Olszewska; Zbigniew Samochocki; Radosław Śpiewak; Aleksandra Wilkowska

doi:10.5114/pja.2020.102084

eISSN: 2391-6052
ISSN: 2353-3854

Alergologia Polska - Polish Journal of Allergology

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abstract:

Special paper

Biological drugs in the treatment of atopic dermatitis – recommendations of the Polish Dermatological Society, the Polish Society of Allergology, the Polish Pediatric Society and the Polish Society of Family Medicine

Roman J. Nowicki

¹

,

Magdalena Trzeciak

¹

,

Lidia Rudnicka

²

,

Jacek Szepietowski

³

,

Marek Kulus

⁴

,

Maciej Kupczyk

⁵

,

Agnieszka Mastalerz-Migas

⁶

,

Jarosław Peregud-Pogorzelski

⁷

,

Karina Jahnz-Różyk

⁸

,

Joanna Narbutt

⁹

,

Magdalena Czarnecka-Operacz

¹⁰

,

Rafal Czajkowski

¹¹

,

Elżbieta Grubska-Suchanek

¹

,

Dorota Krasowska

¹²

,

Beata Kręcisz

¹³

,

Cezary Kowalewski

¹⁴

,

Aleksandra Lesiak

⁸

,

Malgorzata Olszewska

²

,

Zbigniew Samochocki

²

,

Radosław Śpiewak

¹⁵

,

Aleksandra Wilkowska

¹

Katedra i Klinika Dermatologii, Wenerologii i Alergologii, Gdański Uniwersytet Medyczny, Polska
Katedra i Klinika Dermatologiczna, Warszawski Uniwersytet Medyczny, Warszawa, Polska
Katedra i Klinika Dermatologii, Wenerologii i Alergologii, Uniwersytet Medyczny im. Piastów Śłąskich we Wrocławiu, Polska
Klinika Pneumonologii i Alergologii Wieku Dziecięcego, Warszawski Uniwersytet Medyczny, Warszawa, Polska
Klinika Chorób Wewnętrznych, Astmy i Alergii, Uniwersytet Medyczny w Łodzi, Polska
Katedra i Zakład Medycyny Rodzinnej, Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Polska
Klinika Pediatrii i Onkologii Dziecięcej, Pomorski Uniwersytet Medyczny w Szczecinie, Polska
Klinika Chorób Wewnętrznych, Pneumonologii, Alergologii i Immunologii Klinicznej, Wojskowy Instytut Medyczny, Warszawa, Polska
Klinika Dermatologii, Dermatologii Dziecięcej i Onkologicznej, Uniwersytet Medyczny w Łodzi, Polska
Katedra i Klinika Dermatologii, Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Polska
Katedra Dermatologii i Wenerologii, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Uniwersytet Mikołaja Kopernika w Toruniu, Polska
Katedra i Klinika Dermatologii, Wenerologii i Dermatologii Dziecięcej, Uniwersytet Medyczny w Lublinie, Polska
Klinika Dermatologii, Wydział Lekarski i Nauk o Zdrowiu, Uniwersytet Jana Kochanowskiego w Kielcach, Polska
Klinika Dermatologii i Immunodermatologii, Warszawski Uniwersytet Medyczny, Warszawa, Polska
Zakład Dermatologii Doświadczalnej i Kosmetologii, Uniwersytet Jagielloński Collegium Medicum, Kraków, Polska

Alergologia Polska – Polish Journal of Allergology 2020; 7, 4: 171–179

DOI: https://doi.org/10.5114/pja.2020.102084

Online publish date: 2020/12/26

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AMA

Nowicki RJ, Trzeciak M, Rudnicka L, et al. Biological drugs in the treatment of atopic dermatitis – recommendations of the Polish Dermatological Society, 
the Polish Society of Allergology, the Polish Pediatric Society 
and the Polish Society of Family Medicine. Alergologia Polska - Polish Journal of Allergology. 2020;7(4):171-179. doi:10.5114/pja.2020.102084.

APA

Nowicki, R. J., Trzeciak, M., Rudnicka, L., Szepietowski, J., Kulus, M.,  & Kupczyk, M. et al. (2020). Biological drugs in the treatment of atopic dermatitis – recommendations of the Polish Dermatological Society, 
the Polish Society of Allergology, the Polish Pediatric Society 
and the Polish Society of Family Medicine. Alergologia Polska - Polish Journal of Allergology, 7(4), 171-179. https://doi.org/10.5114/pja.2020.102084

Chicago

Nowicki, Roman J, Magdalena Trzeciak, Lidia Rudnicka, Jacek Szepietowski, Marek Kulus, Maciej Kupczyk,  and Agnieszka Mastalerz-Migas et al. 2020. "Biological drugs in the treatment of atopic dermatitis – recommendations of the Polish Dermatological Society, 
the Polish Society of Allergology, the Polish Pediatric Society 
and the Polish Society of Family Medicine". Alergologia Polska - Polish Journal of Allergology 7 (4): 171-179. doi:10.5114/pja.2020.102084.

Harvard

Nowicki, R., Trzeciak, M., Rudnicka, L., Szepietowski, J., Kulus, M., Kupczyk, M., Mastalerz-Migas, A., Peregud-Pogorzelski, J., Jahnz-Różyk, K., Narbutt, J., Czarnecka-Operacz, M., Czajkowski, R., Grubska-Suchanek, E., Krasowska, D., Kręcisz, B., Kowalewski, C., Lesiak, A., Olszewska, M., Samochocki, Z., Śpiewak, R.,  and Wilkowska, A. (2020). Biological drugs in the treatment of atopic dermatitis – recommendations of the Polish Dermatological Society, 
the Polish Society of Allergology, the Polish Pediatric Society 
and the Polish Society of Family Medicine. Alergologia Polska - Polish Journal of Allergology, 7(4), pp.171-179. https://doi.org/10.5114/pja.2020.102084

MLA

Nowicki, Roman et al. "Biological drugs in the treatment of atopic dermatitis – recommendations of the Polish Dermatological Society, 
the Polish Society of Allergology, the Polish Pediatric Society 
and the Polish Society of Family Medicine." Alergologia Polska - Polish Journal of Allergology, vol. 7, no. 4, 2020, pp. 171-179. doi:10.5114/pja.2020.102084.

Vancouver

Nowicki R, Trzeciak M, Rudnicka L, Szepietowski J, Kulus M, Kupczyk M et al. Biological drugs in the treatment of atopic dermatitis – recommendations of the Polish Dermatological Society, 
the Polish Society of Allergology, the Polish Pediatric Society 
and the Polish Society of Family Medicine. Alergologia Polska - Polish Journal of Allergology. 2020;7(4):171-179. doi:10.5114/pja.2020.102084.

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The basis for development of atopic dermatitis are genetic, immunological and microbiological abnormalities as well as epidermal barrier defects. The course of the disease includes periodic exacerbations and remissions. Its development and course are influenced by numerous environmental and individual factors. In recent decades, in industrialized countries, a threefold increase in the incidence of atopic dermatitis was observed. There also is an increasing number of cases resistant to topical treatment. Effective treatment of atopic dermatitis should provide control of clinical symptoms, prevent exacerbations and improve the quality of life of patients. The multifactorial etiopathogenesis and various endotypes and phenotypes of the disease justify the tendency to optimize and personalize the therapy. Currently, we recommend the use of dupilumab for the treatment of patients from 12 years of age with moderate and severe atopic dermatitis, who do not respond to topical treatment.

keywords:

Biological drugs in the treatment of atopic dermatitis – recommendations of the Polish Dermatological Society, the Polish Society of Allergology, the Polish Pediatric Society and the Polish Society of Family Medicine

biological drugs, dupilumab, atopic dermatitis, therapeutic recommendations