Bullous skin lesion reaction as an example of an adverse effect of a preparation containing 0.1% octenidine dihydrochloride and 2% phenoxyethanol (Octenisept®)

Agnieszka Hołdrowicz; Joanna Narbutt; Cezary Pałczyński; Izabela Kupryś-Lipińska; Aleksandra Lesiak

doi:10.5114/dr.2018.80845

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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6/2018
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abstract:

Case report

Bullous skin lesion reaction as an example of an adverse effect of a preparation containing 0.1% octenidine dihydrochloride and 2% phenoxyethanol (Octenisept®)

Agnieszka Hołdrowicz

,

Joanna Narbutt

,

Cezary Pałczyński

,

Izabela Kupryś-Lipińska

,

Aleksandra Lesiak

Dermatol Rev/Przegl Dermatol 2018, 105, 753–760

DOI: https://doi.org/10.5114/dr.2018.80845

Online publish date: 2019/01/04

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AMA

Hołdrowicz A, Narbutt J, Pałczyński C, Kupryś-Lipińska I, Lesiak A. Bullous skin lesion reaction as an example of an adverse effect of a preparation containing 0.1% octenidine dihydrochloride and 2% phenoxyethanol (Octenisept®). Dermatology Review/Przegląd Dermatologiczny. 2018;105(6):753-760. doi:10.5114/dr.2018.80845.

APA

Hołdrowicz, A., Narbutt, J., Pałczyński, C., Kupryś-Lipińska, I.,  & Lesiak, A. (2018). Bullous skin lesion reaction as an example of an adverse effect of a preparation containing 0.1% octenidine dihydrochloride and 2% phenoxyethanol (Octenisept®). Dermatology Review/Przegląd Dermatologiczny, 105(6), 753-760. https://doi.org/10.5114/dr.2018.80845

Chicago

Hołdrowicz, Agnieszka, Joanna Narbutt, Cezary Pałczyński, Izabela Kupryś-Lipińska,  and Aleksandra Lesiak. 2018. "Bullous skin lesion reaction as an example of an adverse effect of a preparation containing 0.1% octenidine dihydrochloride and 2% phenoxyethanol (Octenisept®)". Dermatology Review/Przegląd Dermatologiczny 105 (6): 753-760. doi:10.5114/dr.2018.80845.

Harvard

Hołdrowicz, A., Narbutt, J., Pałczyński, C., Kupryś-Lipińska, I.,  and Lesiak, A. (2018). Bullous skin lesion reaction as an example of an adverse effect of a preparation containing 0.1% octenidine dihydrochloride and 2% phenoxyethanol (Octenisept®). Dermatology Review/Przegląd Dermatologiczny, 105(6), pp.753-760. https://doi.org/10.5114/dr.2018.80845

MLA

Hołdrowicz, Agnieszka et al. "Bullous skin lesion reaction as an example of an adverse effect of a preparation containing 0.1% octenidine dihydrochloride and 2% phenoxyethanol (Octenisept®)." Dermatology Review/Przegląd Dermatologiczny, vol. 105, no. 6, 2018, pp. 753-760. doi:10.5114/dr.2018.80845.

Vancouver

Hołdrowicz A, Narbutt J, Pałczyński C, Kupryś-Lipińska I, Lesiak A. Bullous skin lesion reaction as an example of an adverse effect of a preparation containing 0.1% octenidine dihydrochloride and 2% phenoxyethanol (Octenisept®). Dermatology Review/Przegląd Dermatologiczny. 2018;105(6):753-760. doi:10.5114/dr.2018.80845.

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Introduction
Octenisept^® is an antiseptic solution which is intended to be applied on the skin, mucous membranes and wounds.

Objective
To present a case study of a bullous skin lesions, which occurred in a 4-year-old girl after Octenisept^® application, and to highlight various possible side effects of this preparation.

Case report
In a 4-year-old girl Octenisept^® was applied preventively three times at intervals of 12 hours on an epidermal abrasion. Erythema and hydropic papules emerged 6–8 hours after application and were followed by vesicles and bullae 8 hours later. In spite of the topical treatment with glucocorticoids and an antibiotic, the lesions persisted for several weeks.

Conclusions
Taking into consideration the wide usage of Octenisept^® in many fields of medicine, there is a need to conduct further research on the allergic potential and toxicity of this product.

keywords:

Bullous skin lesion reaction as an example of an adverse effect of a preparation containing 0.1% octenidine dihydrochloride and 2% phenoxyethanol (Octenisept®)

Agnieszka Hołdrowicz , Joanna Narbutt , Cezary Pałczyński , Izabela Kupryś-Lipińska , Aleksandra Lesiak

adverse effects, Octenisept®, bullous skin lesion reaction

Agnieszka Hołdrowicz

,

Joanna Narbutt

,

Cezary Pałczyński

,

Izabela Kupryś-Lipińska

,

Aleksandra Lesiak

adverse effects, Octenisept^®, bullous skin lesion reaction