eISSN: 1897-4252
ISSN: 1731-5530
Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery
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2/2015
vol. 12
 
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abstract:

CASE REPORTS
Atopic allergy and chronic inflammation of the oral mucosa in a 4-year-old boy after heart transplantation – diagnostic and therapeutic difficulties

Edyta Machura
,
Beata Chodór
,
Magdalena Kleszyk
,
Małgorzata Pindycka-Piaszczyńska
,
Ewelina Chrobak
,
Jacek Białkowski

Kardiochirurgia i Torakochirurgia Polska 2015; 12 (2): 176-180
DOI: https://doi.org/10.5114/kitp.2015.52866
Online publish date: 2015/07/10
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In recent years, we have been observing an increased proportion of atopic diseases in children after solid organ transplantation. The pathogenesis of post-transplantation allergy is not completely understood and probably involves several factors, including immunosuppressive therapy. In this paper we present a case of 3-year old boy, after orthotopic heart transplantation at 6 months of age, with symptoms of food allergy associated with atopic dermatitis and changes in the orofacial area. The mentioned symptoms and elevated levels of total and specific IgE occurred with a year of transplant. Because of failure to achieve remission after typical allergy therapy we suspected that the reason of allergy in this case can be immunosuppressive therapy.
keywords:

children, atopic dermatitis, heart transplantation, tacrolimus, post-transplantation allergy
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