Cardiac rupture in takotsubo cardiomyopathy treated surgically

A 74-year-old woman, without a history of cardiological problems or risk factors of cardiovascular diseases, was admitted to the emergency room of our hospital after 2 h of chest pain. During the transport, the patient received 5000 U of unfractionated heparin, aspirin (300 mg) and clopidogrel (600 mg). The patient had suffered from an anxiety syndrome for several years.
At admission, the patient was in a serious condition generally, was vomiting, and had severe chest pain with signs of cardiogenic shock (skin pale and wet, blood presure (BP) and heart rate (HR) undetectable). Electrocardiogram demonstrated a sinus rhythm of 58 per minute with QS complex and ST segment elevation in precordial leads (V2–V6). Laboratory results revealed increased troponin I concentration (2.041 ng/ml). Following hemodynamic stabilization, the patient was transported to the catheterization laboratory. Coronarography did not reveal any significant stenosis. Left ventricle angiography (LVA) showed normal volume with contractile disturbances of apex and hyperkinesis of the basement segments, with ejection fraction (EF) of 56%. Contrast outflow to the epicardium was observed within the area of the apex, through the perforated wall of the left ventricle (Figures 1 A–C). Echo confirmed the presence of fluid in the pericardium and cardiac tamponade. The patient was supported with intra-aortic balloon contra-pulsation and transported to the cardiac surgery for urgent intervention. During transport, the patient lost consciousness. After urgent cardiac tamponade decompression, the pulse and arterial pressure increased. Active bleeding through the ruptured left ventricle was observed in the area of the apex during the operation. Left ventricular plication with sutures on a double layered Teflon pad was performed. The lines of the sutures were conducted through healthy tissues. Examination of the supported ruptured region showed left ventricle tightness and complete hemostasis. No significant complications were observed during the perioperative period. On the first day after the operation the patient was extubated, and on the fifth day the intra-aortic balloon contra-pulsation was removed. The patient was transported to the regional hospital on day 11 to continue the therapeutic and rehabilitation procedures. A discharge echocardiogram revealed akinesis of the apex and hypokinesis of the septum, with an EF of 50%. The patient was under cardiosurgical follow-up for the next 3...


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