eISSN: 1897-4295
ISSN: 1734-9338
Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej
Current issue Archive Manuscripts accepted About the journal Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
Editorial Policies
Sarajevo Declaration on Integrity and Visibility of Scholarly Publications
3/2024
vol. 20
 
Share:
Send email
Share:
abstract:
Original paper

Cardiac troponin I release after transcatheter closure of atrial septal defects is associated with supraventricular arrhythmias on early follow-up

Paweł Prochownik
1
,
Klaudia Bielecka
1
,
Tadeusz Przewłocki
1
,
Zuzanna Sachajko
2
,
Urszula Gancarczyk
1
,
Piotr Wilkołek
1
,
Michał Tworek
1
,
Piotr Podolec
1
,
Larysa Bielecka
2
,
Monika Komar
1

  1. Department of Cardiac and Vascular Diseases, John Paul II Hospital, Institute of Cardiology, Krakow, Poland
  2. Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland
Adv Interv Cardiol 2024; 20, 3 (77): 338–344
DOI: https://doi.org/10.5114/aic.2024.142326
Online publish date: 2024/08/14
View full text Get citation
 
Introduction:
Atrial septal defects (ASD) are prevalent congenital heart anomalies found in the adult population. Percutaneous ASD closure has become a routine clinical practice. Elevation of postprocedural transient cardiac biomarkers and exacerbation of supraventricular arrhythmias have been reported in the subject literature.

Aim:
To explore the relationship between cardiac troponin I (cTnI) elevation and supraventricular ectopy (SVE) following percutaneous closure of secundum atrial septal defect (ASD) in adult patients.

Material and methods:
600 consecutive patients who underwent successful transcatheter ASD secundum closure were analyzed. Serum levels of cTnI were measured before and within 72 h of device implantation. 24-hour Holter monitoring was performed before the procedure, at 1 month, and at 6 months of follow-up.

Results:
SVE burden increased 1 month after the procedure (median 1021.00; min.–max. 11.00–29 862.00) compared to baseline values (median 146.00; min.–max. 0–1865.00; p < 0.01). 61.7% of patients demonstrated a cTnI rise exceeding 50% of the upper reference limit within 24 h of the procedure. A statistically significant positive correlation between SVE burden 1 month after the procedure and periprocedural cTnI increase (p < 0.05, r = 0.41) was observed, while cTnI levels significantly correlated with procedure and fluoroscopy time (p < 0.001), device size (p < 0.001) and maximal ASD diameter (p < 0.001).

Conclusions:
A significant increase of cTnI is noted frequently after transcatheter ASD closure and seems to predict exacerbation in SVE burden on short-term follow up. The independent risk factors of cTnI rise are prolonged procedure duration and larger device sizes.

keywords:

electrocardiography, arrhythmia, echocardiography, interventional cardiology, congenital heart disease, myocardial damage
Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2024 Termedia Sp. z o.o.
Developed by Bentus.