Case report<br>Can biologic treatment induce cutaneous focal mucinosis?

Aleksandra Lesiak; Marcin Włodarczyk; Aleksandra Sobolewska; Joanna Sieniawska; Michał Rogowski-Tylman; Anna Sysa-Jedrzejowska; Irmina Olejniczak-Staruch; Joanna Narbutt

doi:10.5114/pdia.2014.40944

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

Current issue Archive Manuscripts accepted About the journal Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

6/2014
vol. 31

Send email

Copy url:

abstract:

Case report
Can biologic treatment induce cutaneous focal mucinosis?

Aleksandra Lesiak

,

Marcin Włodarczyk

,

Aleksandra Sobolewska

,

Joanna Sieniawska

,

Michał Rogowski-Tylman

,

Anna Sysa-Jedrzejowska

,

Irmina Olejniczak-Staruch

,

Joanna Narbutt

Postep Derm Alergol 2014; XXXI, 6: 413–416

DOI: https://doi.org/10.5114/pdia.2014.40944

Online publish date: 2014/12/03

View full text Get citation

EndNote

Papers, Reference Manager, RefWorks, Zotero

AMA

Lesiak A, Włodarczyk M, Sobolewska A, et al. Case reportCan biologic treatment induce cutaneous focal mucinosis?. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2014;31(6):413-416. doi:10.5114/pdia.2014.40944.

APA

Lesiak, A., Włodarczyk, M., Sobolewska, A., Sieniawska, J., Rogowski-Tylman, M.,  & Sysa-Jedrzejowska, A. et al. (2014). Case reportCan biologic treatment induce cutaneous focal mucinosis?. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 31(6), 413-416. https://doi.org/10.5114/pdia.2014.40944

Chicago

Lesiak, Aleksandra, Marcin Włodarczyk, Aleksandra Sobolewska, Joanna Sieniawska, Michał Rogowski-Tylman, Anna Sysa-Jedrzejowska,  and Irmina Olejniczak-Staruch et al. 2014. "Case reportCan biologic treatment induce cutaneous focal mucinosis?". Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii 31 (6): 413-416. doi:10.5114/pdia.2014.40944.

Harvard

Lesiak, A., Włodarczyk, M., Sobolewska, A., Sieniawska, J., Rogowski-Tylman, M., Sysa-Jedrzejowska, A., Olejniczak-Staruch, I.,  and Narbutt, J. (2014). Case reportCan biologic treatment induce cutaneous focal mucinosis?. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 31(6), pp.413-416. https://doi.org/10.5114/pdia.2014.40944

MLA

Lesiak, Aleksandra et al. "Case reportCan biologic treatment induce cutaneous focal mucinosis?." Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, vol. 31, no. 6, 2014, pp. 413-416. doi:10.5114/pdia.2014.40944.

Vancouver

Lesiak A, Włodarczyk M, Sobolewska A, Sieniawska J, Rogowski-Tylman M, Sysa-Jedrzejowska A et al. Case reportCan biologic treatment induce cutaneous focal mucinosis?. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2014;31(6):413-416. doi:10.5114/pdia.2014.40944.

Skin mucinosis is a rare skin disease which clinically manifests as firm papules and waxy nodules. We report a case of a 66-year-old female psoriatic patient who developed skin mucinosis during biological therapy. Because of a previous lack of response to the local and conventional systemic treatment of psoriasis, the patient received biological therapy (infliximab from June 2008 to May 2009 – initial clinical improvement and loss of treatment effectiveness in the 36th week of the therapy; adalimumab from June 2009 to January 2010 – lack effectiveness; ustekinumab from March 2012 to the present). Throughout 2 months we observed a manifestation of the skin mucinosis as well-demarcated, yellow and brown, papulo-nodular lesions of 5–10 mm in diameter, localized on the back. Histopathological examination with alcian blue staining demonstrated mucin deposits in the dermis. On the basis of clinical and histopathological findings, the diagnosis of cutaneous focal mucinosis was established. We present the case because of the extremely rare occurrence of the disease. Scarce literature and data suggest that there is an association between focal mucinosis and thyroid dysfunction, as well as possible adverse effects of biological therapy with TNF-α antagonists.

keywords:

Case reportCan biologic treatment induce cutaneous focal mucinosis?

Aleksandra Lesiak , Marcin Włodarczyk , Aleksandra Sobolewska , Joanna Sieniawska , Michał Rogowski-Tylman , Anna Sysa-Jedrzejowska , Irmina Olejniczak-Staruch , Joanna Narbutt

skin mucinosis, TNF-α antagonists, adverse effects, biological therapy, psoriasis

Case report
Can biologic treatment induce cutaneous focal mucinosis?

Aleksandra Lesiak

,

Marcin Włodarczyk

,

Aleksandra Sobolewska

,

Joanna Sieniawska

,

Michał Rogowski-Tylman

,

Anna Sysa-Jedrzejowska

,

Irmina Olejniczak-Staruch

,

Joanna Narbutt