eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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1/2012
vol. 29
 
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abstract:

Case report
Effectiveness of interferon α in mycosis fungoides therapy

Monika Sikorska
,
Małgorzata Sokołowska-Wojdyło
,
Anna Kowalczyk
,
Jadwiga Roszkiewicz

Post Dermatol Alergol 2012; XXIX, 1: 51–55
Online publish date: 2012/02/09
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Mycosis fungoides (MF) is the most common form of cutaneous T-cell lymphoma. Skin manifestations are generally the first signs of the disease. Many topical and systemic therapeutic alternatives are utilized in MF treatment, but there is no defined curative treatment regimen. One of the successful agents is interferon-α (IFN-α), which shows appreciable responses, especially in combination therapy with psoralen and ultraviolet A (PUVA). However, the optimal IFN dose, schedule, and duration of therapy are still not determined. We describe 2 patients suffering from MF, being treated at the Clinic of Dermatology, Venereology and Allergology in Gdansk, including IFN and phototherapy with very satisfactory results.
keywords:

interferon-α2a, mycosis fungoides, PUVA, UVB311
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