Chemotherapy for gastric cancer patients – time for personalization in medicine?

Elżbieta Nowara; Agnieszka Boratyn-Nowicka; Anna Polakiewicz-Gilowska; Anna Drosik; Magdalena Kustra; Joanna Huszno

doi:10.5114/wo.2012.27342

eISSN: 1897-4309
ISSN: 1428-2526

Contemporary Oncology/Współczesna Onkologia

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1/2012
vol. 16

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abstract:

Review paper

Chemotherapy for gastric cancer patients – time for personalization in medicine?

Elżbieta Nowara

,

Agnieszka Boratyn-Nowicka

,

Anna Polakiewicz-Gilowska

,

Anna Drosik

,

Magdalena Kustra

,

Joanna Huszno

Wspolczesna Onkol 2012; 16 (1): 86–89

DOI: https://doi.org/10.5114/wo.2012.27342

Online publish date: 2012/02/29

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Gastric cancer is one of the most frequent neoplasms. Although the incidence of gastric cancer worldwide has declined, there is still high mortality. Treatment of inoperable disease is under evaluation in clinical trials. In palliative treatment chemotherapy containing cisplatin and 5-fluorouracil is the most widely used. In the past years progress in tumour biology has advanced greatly and has led to development of new molecules aimed at targets important for cancer expansion. There are several randomized trials under targeted therapies for gastric cancer patients. One of them led to approval of trastuzumab. In the current paper the authors illustrate new possibilities in systemic treatment with particular attention to targeted therapy and personalization in medicine.

keywords:

Chemotherapy for gastric cancer patients – time for personalization in medicine?

Elżbieta Nowara , Agnieszka Boratyn-Nowicka , Anna Polakiewicz-Gilowska , Anna Drosik , Magdalena Kustra , Joanna Huszno

gastric cancer, chemotherapy, targeted therapy, personalization in medicine

Elżbieta Nowara

,

Agnieszka Boratyn-Nowicka

,

Anna Polakiewicz-Gilowska

,

Anna Drosik

,

Magdalena Kustra

,

Joanna Huszno