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Family Medicine & Primary Care Review
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1/2023
vol. 25
 
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Original paper

Clinical approach to the differential diagnosis between immune-mediated diabetes and type 2 diabetes in adult patients

Barbara Biniek
1
,
Marcin Kosiński
1
,
Monika Żurawska-Kliś
1
,
Anna Wojtczak
1
,
Katarzyna Cypryk
1

  1. Department of Internal Medicine and Diabetology, Medical University of Lodz, Poland
Family Medicine & Primary Care Review 2023; 25(1): 18–24
Online publish date: 2023/03/31
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1. Ahlqvist E, Storm P, Käräjämäki A, et al. Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables. Lancet Diabetes Endocrinol 2018; 6(5): 361–369.
2. Naik RG, Brooks-Worrell BM, Palmer JP. Latent autoimmune diabetes in adults. J Clin Endocrinol Metab 2009; 94(12): 4635–4644.
3. Rolandsson O, Palmer JP. Latent autoimmune diabetes in adults (LADA) is dead: long live autoimmune diabetes! Diabetologia 2010; 53(7): 1250–1253.
4. Gale EA. Latent autoimmune diabetes in adults: a guide for the perplexed. Diabetologia 2005; 48(11): 2195–2199.
5. Hawa MI, Kolb H, Schloot N, et al. Adult-onset autoimmune diabetes in Europe is prevalent with a broad clinical phenotype: Action LADA 7. Diabetes Care 2013; 36(4): 908–913.
6. Buzzetti R, Tuomi T, Mauricio D, et al. Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement from an International Expert Panel. Diabetes 2020; 69(10): 2037–2047.
7. Zimmet PZ, Tuomi T, Mackay IR, et al. Latent autoimmune diabetes mellitus in adults (LADA): the role of antibodies to glutamic acid decarboxylase in diagnosis and prediction of insulin dependency. Diabet Med 1994; 11(3): 299–303.
8. Fourlanos S, Perry C, Stein MS, et al. A clinical screening tool identifies autoimmune diabetes in adults. Diabetes Care 2006; 29(5): 970–975.
9. Polish Diabetes Association. 2020 Guidelines on the management of diabetic patients. A position of Diabetes Poland. Clinical Diabetology 2020; 9: 1–101.
10. Fourlanos S, Dotta F, Greenbaum CJ, et al. Latent autoimmune diabetes in adults (LADA) should be less latent. Diabetologia 2005; 48(11): 2206–2212.
11. Cernea S, Buzzetti R, Pozzilli P. Beta-cell protection and therapy for latent autoimmune diabetes in adults. Diabetes Care 2009; 32(Suppl. 2): S246–S252.
12. Brophy S, Yderstraede K, Mauricio D, et al. Time to insulin initiation cannot be used in defining latent autoimmune diabetes in adults. Diabetes Care 2008; 31(3): 439–441.
13. Chaillous L, Bouhanick B, Kerlan V, et al. Clinical and metabolic characteristics of patients with latent autoimmune diabetes in adults (LADA): absence of rapid beta-cell loss in patients with tight metabolic control. Diabetes Metab 2010; 36(1): 64–70.
14. Thunander M, Thorgeirsson H, Törn C, et al. β-cell function and metabolic control in latent autoimmune diabetes in adults with early insulin versus conventional treatment: a 3-year follow-up. Eur J Endocrinol 2011; 164(2): 239–245.
15. Schloot N, Eisenbarth GS. Isohormonal therapy of endocrine autoimmunity. Immunol Today 1995; 16(6): 289–294.
16. Aaen K, Rygaard J, Josefsen K, et al. Dependence of antigen expression on functional state of beta-cells. Diabetes 1990; 39(6): 697–701.
17. Zinman B, Kahn SE, Haffner SM, et al. Phenotypic characteristics of GAD antibody-positive recently diagnosed patients with type 2 diabetes in North America and Europe. Diabetes 2004; 53(12): 3193–3200.
18. Pipi E, Marketou M, Tsirogianni A. Distinct clinical and laboratory characteristics of latent autoimmune diabetes in adults in relation to type 1 and type 2 diabetes mellitus. World J Diabetes 2014; 5(4): 505–510.
19. Yohena S, Penas-Steinhardt A, Muller C, et al. Immunological and clinical characteristics of latent autoimmune diabetes in the elderly. Diabetes Metab Res Rev 2019; 35(5): e3137.
20. Lutgens MW, Meijer M, Peeters B, et al. Easily obtainable clinical features increase the diagnostic accuracy for latent autoimmune diabetes in adults: an evidence-based report. Prim Care Diabetes 2008; 2(4): 207–211.
21. Appel SJ, Wadas TM, Rosenthal RS, et al. Latent autoimmune diabetes of adulthood (LADA): an often misdiagnosed type of diabetes mellitus. J Am Acad Nurse Pract 2009; 21(3): 156–159.
22. Cousminer DL, Ahlqvist E, Mishra R, et al. First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes. Diabetes Care 2018; 41(11): 2396–2403.
23. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2020. Diabetes Care 2020; 43: S14–S31.
24. World Health Organization [editorial]. Classification of diabetes mellitus. Geneva: WHO; 2019.
25. Carlsson S. Etiology and Pathogenesis of Latent Autoimmune Diabetes in Adults (LADA) Compared to Type 2 Diabetes. Front Physiol 2019; 10: 320.
26. Rasouli B, Andersson T, Carlsson PO, et al. Smoking and the Risk of LADA: Results from a Swedish Population-Based Case-Control Study. Diabetes Care 2016; 39(5): 794–800.
27. Palmer JP, Hampe CS, Chiu H, et al. Is latent autoimmune diabetes in adults distinct from type 1 diabetes or just type 1 diabetes at an older age? Diabetes 2005; 54(Suppl. 2): S62–S67.
28. Pozzilli P, Pieralice S. Latent Autoimmune Diabetes in Adults: Current Status and New Horizons. Endocrinol Metab (Seoul) 2018; 33(2): 147–159.
29. Klingensmith GJ, Pyle L, Arslanian S, et al. The presence of GAD and IA-2 antibodies in youth with a type 2 diabetes phenotype: results from the TODAY study. Diabetes Care 2010; 33(9): 1970–1975.
30. Szepietowska B, Wawrusiewicz-Kurylonek N, Krętowski A, et al. Endocrine autoimmunity in patients with Latent Autoimmune Diabetes in Adults (LADA) – association with HLA genotype. Endokrynol Pol 2016; 67(2): 197–201.
31. Kawasaki E. Type 1 diabetes and autoimmunity. Clin Pediatr Endocrinol 2014; 23(4): 99–105.
Copyright: © 2023 Family Medicine & Primary Care Review. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
 
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