Clinical efficacy of ciprofloxacin 0,3% (Ciloxan) in the treatment of bacterial infections of external eye segment

Introduction
The main subject of the study was to evaluate efficacy of ciprofloxacin 0,3% ophthalmic solution (Ciloxan) in the treatment of bacterial conjunctivitis and surgical prophylaxis. Safety and comfort of topical ciprofloxacin treatment was also examined.

Material and methods
Two study arms: 99 patients with bacterial conjunctivitis (A group) and 48 patients awaiting cataract surgery (B group – total 147 subjects in both groups) received ciprofloxacin 0,3% ophthalmic solution (Ciloxan) 4 doses a day for seven days. Bacteriological evaluation was established before and after treatment for each eye.

Results
95 out of the 99 patients (96%) in the first arm were completely cured (all signs and symptoms of the bacterial conjunctivitis were eliminated). In the second arm complete eradication of bacterial flora was achieved in 46 out of 48 pretreated patients (96%).

Conclusions
Topical ciprofloxacin 0,3% (iloxan) was found very effective and fast in reduction of typical signs and symptoms of bacterial conjunctivitis as well as in eradication of bacterial flora before surgery treatment.