eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
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3/2009
vol. 34
 
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abstract:

Clinical immunology
Evaluation of immunological criteria for rheumatoid arthritis

A. Havryluk
,
R. Bilyy
,
J. Tolstiak
,
I. Kril
,
M. Synenka
,
J. Ząbek
,
A. Palacz
,
J. Bogaczewicz
,
V. Chopyak
,
R. Stoika

Centr Eur J Immunol 2009; 34 (3): 176-181
Online publish date: 2009/09/28
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Measurement of specific autoantibodies in RA patients cannot be considered as a universal marker of this immunopathological process. Generally accepted laboratory immunological testing algorithm is not sufficient for RA patients. There is no correlation between the expression of early and late markers of lymphocyte apoptosis.
In RA patients there is a positive correlation between the titer of lectin-induced agglutination and expression of lymphocyte activation markers. Evaluation of lectin-induced apoptosis of lymphocytes allows early detection of RA and improvement of chemotherapy scheme.
keywords:

rheumatoid arthritis, autoantibodies, markers of lymphocyte apoptosis and activation, lectin-induced agglutination
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