eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
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2/2009
vol. 34
 
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abstract:

Clinical immunology
Neutrophil function in the patient with common variable immunodeficiency – case report

Aleksandra Lewandowicz-Uszyńska
,
Bożena Polańska
,
Jerzy Świerkot
,
Maryla Kazimierowska-Niemczuk
,
Jacek Szechiński
,
Adam Jankowski

Centr Eur J Immunol 2009; 34 (2): 113-117
Online publish date: 2009/05/20
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Chosen parameters assessing neutrophil function (myeloperoxidase – MPO concentration, elastase concentration, phagocytic test and oxygen metabolism of neutrophils) in 38 year old patient diagnosed with CVID are presented. The examinations were carried out before the first infusion of IVIG and on the second day after infusion. Before IVIG substitution increased MPO serum concentration was found, enhanced total phagocytic skills and strongly suppressed oxygen metabolism of neutrophils measured by the chemiluminescency test. IVIG substitution improved both spontaneous and stimulated neutrophil chemiluminescence (CL).
keywords:

metabolic activity of neutrophils, common variable immunodeficiency
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