Combined impact of local anaesthetic infiltration through wound catheter and epidural analgesia following surgical hepatectomy: a meta-analysis

Gang Shao; Shuwei Chen

doi:10.5114/wiitm.2024.135810

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Anaesthesiology

abstract:

Systematic review/Meta-analysis

Combined impact of local anaesthetic infiltration through wound catheter and epidural analgesia following surgical hepatectomy: a meta-analysis

Gang Shao

¹

,

Shuwei Chen

¹

Department of Anesthesiology, The First People’s Hospital of Fuyang Hangzhou, Fuyang District, Hangzhou, China

Videosurgery Miniinv 2024; 19 (1): 25–31

DOI: https://doi.org/10.5114/wiitm.2024.135810

Online publish date: 2024/02/27

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Introduction
A meta-analysis was performed to examine the effects of wound catheter (WC) local anaesthetic infiltration (LAI) and epidural analgesia (EA) in open hepatectomy (OH).

Material and methods
A systematic literature review was performed, which found 350 subjects with OH at the baseline of the studies; 159 of them were treated with WC local anaesthetic infiltration, and 191 used EA.

Results
WC LAI substantially reduced the functional recovery time (MD = –0.64; 95% CI, –1.02 to –0.26, p < 0.001) and increased the pain score on the second postoperative day (MD = 0.25; 95% CI: 0.10–0.40, p < 0.001) compared to EA in OH patients. WC LAI did not vary from EA in OH patients in second postoperative opiate use (MD = –14.86; 95% CI: –32.88 to 3.16, p = 0.11) or overall complication rate (OR = 0.66; 95% CI: 0.41–1.04, p = 0.07).

Conclusions
WC LAI showed a non-significant difference in opiate consumption on the second postoperative day and in the overall complication rate, compared with EA, but it showed a lower functional recovery time and higher pain score.

keywords:

open hepatectomy, wound catheter local anaesthetic infiltration, epidural analgesia, opiate consumption on the second postoperative day, overall complication rate, pain score on the second postoperative day

Combined impact of local anaesthetic infiltration through wound catheter and epidural analgesia following surgical hepatectomy: a meta-analysis

Gang Shao 1 , Shuwei Chen 1

open hepatectomy, wound catheter local anaesthetic infiltration, epidural analgesia, opiate consumption on the second postoperative day, overall complication rate, pain score on the second postoperative day

Gang Shao

¹

,

Shuwei Chen

¹