eISSN: 1897-4295
ISSN: 1734-9338
Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej
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4/2023
vol. 19
 
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abstract:
Original paper

Comparison of outcomes in patients with severe aortic stenosis treated with small and large Medtronic Evolut R and Evolut PRO self-expandable prosthetic valves

Krzysztof Wilczek
1
,
Piotr Chodór
2
,
Jan Harpula
3
,
Tomasz Hrapkowicz
4
,
Łukasz Włoch
2
,
Karolina Chodór-Rozwadowska
2
,
Grzegorz Honisz
2
,
Mariusz Gąsior
1
,
Zbigniew Kalarus
2

  1. 3rd Department of Cardiology, Medical University of Silesia in Katowice, Silesian Center for Heart Diseases in Zabrze, Poland
  2. Department of Cardiology, Congenital Heart Diseases and Electrotherapy, Medical University of Silesia in Katowice, Silesian Center for Heart Diseases in Zabrze, Poland
  3. Division of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland
  4. Department of Cardiac Surgery and Transplantology, Medical University of Silesia in Katowice, Silesian Center for Heart Diseases in Zabrze, Poland
Adv Interv Cardiol 2023; 19, 4 (74): 359–366
DOI: https://doi.org/10.5114/aic.2023.133810
Online publish date: 2023/12/22
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Introduction:
Indications for transcatheter aortic valve implantation (TAVI) continue to expand. Very often TAVI must be done in large annuli. Implantation of the bigger prostheses is often associated with more procedural problems, which may affect the outcomes.

Material and methods:
To compare the outcomes of TAVI procedures using the self-expandable Medtronic Evolut R 34 with the smaller Evolut R or Evolut Pro 23, 26 or 29.

Results:
EuroSCORE II was 5.59 in group I vs 7.87 in group II (p = 0.02). The oversizing rate was higher in group II: 24.1% vs. 18.5% (p < 0.001). The procedure and fluoroscopy times were longer in group II: 209 vs. 187 min (p = 0.03), 44 vs. 27 min (p = 0.01). Moderate paravalvular leak was found more frequently in group II: 5 v 1 (p = 0.04). There was less device success in group II: 22 (78.57%) vs. 57 (96.6%) (p = 0.05). Early safety criteria were similar in both groups: 52 (88.1%) and 24 (92.3%) (p = 0.56). 30-day mortality was similar: 4 (6.7%) vs. 0 in group I and II respectively (p = 0.16).

Conclusions:
TAVI procedures in patients requiring an Evolut R 34 prosthesis are more challenging than in those who need smaller valves. Paravalvular leaks are more frequently observed after TAVI with Evolut R 34, which results in lower device success.

keywords:

aortic stenosis, transcatheter aortic valve implantation, paravalvular leak, self-expandable prosthesis
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