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ISSN: 1233-9687
Polish Journal of Pathology
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2/2010
vol. 61
 
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Refractory anaemia with ringed sideroblasts associated with marked thrombocytosis (RARS-T) with superimposed 5q-syndrome

Mateusz Ziarkiewicz
,
Jadwiga Dwilewicz-Trojaczek
,
Anna Pastwińska
,
Elżbieta Chmarzyńska
,
Małgorzata Paszkowska-Kowalewska
,
Łukasz Koperski
,
Wiesław Wiktor Jędrzejczak
,
Bogna Ziarkiewicz-Wróblewska

POL J PATHOL 2010; 2: 105-109
Online publish date: 2010/09/14
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Refractory anaemia with ringed sideroblasts associated with marked thrombocytosis (RARS-T) is a rare entity belonging to myeloproliferative/myelodysplastic syndromes. Myelodysplastic syndrome (MDS) with isolated del(5q) is a category of MDS characterized by better prognosis and specific morphology. Herein we describe a 69-year-old male with anaemia and thrombocytosis presenting with coexisting features of both these rare diseases. After the description of the clinical data, we summarize the histopathologic, cytogenetic and molecular findings, as well as introduced treatment. Next, we discuss possible diagnostic options with reference to the relevant literature.
keywords:

RARS-T, 5q- syndrome, MDS with isolated del(5q)
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