Could maintenance topical tacrolimus treatment be regarded  as a new therapeutic option in atopic dermatitis?

Joanna Narbutt; Marcin Zakrzewski; Aleksandra Lesiak

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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3/2009
vol. 96

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abstract:

Review paper

Could maintenance topical tacrolimus treatment be regarded as a new therapeutic option in atopic dermatitis?

Joanna Narbutt

,

Marcin Zakrzewski

,

Aleksandra Lesiak

Przegl Dermatol 2009, 96, 235–239

Online publish date: 2009/06/22

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Atopic dermatitis (AD) is a chronic skin disease in which pathogenesis genetic and immunological disturbances are involved. Commonly, AD treatment includes: emollients, topical anti-inflammatory medications and, in severe cases, photo(chemo)therapy or systemic immunosuppressants. Recent literature data indicate the efficacy of maintenance treatment of AD with local tacrolimus applied 2-3 times weekly for several months. In the article current knowledge on this new therapeutic option is described. Moreover, controversies concerning safety of topical calcineurin inhibitors are discussed.

keywords:

Could maintenance topical tacrolimus treatment be regarded as a new therapeutic option in atopic dermatitis?

Joanna Narbutt , Marcin Zakrzewski , Aleksandra Lesiak

atopic dermatitis, tacrolimus, maintenance treatment

Joanna Narbutt

,

Marcin Zakrzewski

,

Aleksandra Lesiak