Cross-sensitization to Artemisia and Ambrosia pollen allergens in an area located outside of the current distribution range of Ambrosia

Łukasz Grewling; Dorota Jenerowicz; Paweł Bogawski; Matt Smith; Małgorzata Nowak; Agata Frątczak; Magdalena Czarnecka-Operacz

doi:10.5114/ada.2018.73167

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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Original paper

Cross-sensitization to Artemisia and Ambrosia pollen allergens in an area located outside of the current distribution range of Ambrosia

Łukasz Grewling

,

Dorota Jenerowicz

,

Paweł Bogawski

,

Matt Smith

,

Małgorzata Nowak

,

Agata Frątczak

,

Magdalena Czarnecka-Operacz

Adv Dermatol Allergol 2018; XXXV (1): 83-89

DOI: https://doi.org/10.5114/ada.2018.73167

Online publish date: 2018/02/20

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AMA

Grewling Ł, Jenerowicz D, Bogawski P, et al. Cross-sensitization to Artemisia and Ambrosia pollen allergens in an area located outside of the current distribution range of Ambrosia. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2018;35(1):83-89. doi:10.5114/ada.2018.73167.

APA

Grewling, Ł., Jenerowicz, D., Bogawski, P., Smith, M., Nowak, M.,  & Frątczak, A. et al. (2018). Cross-sensitization to Artemisia and Ambrosia pollen allergens in an area located outside of the current distribution range of Ambrosia. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 35(1), 83-89. https://doi.org/10.5114/ada.2018.73167

Chicago

Grewling, Łukasz, Dorota Jenerowicz, Paweł Bogawski, Matt Smith, Małgorzata Nowak, Agata Frątczak,  and Magdalena Czarnecka-Operacz. 2018. "Cross-sensitization to Artemisia and Ambrosia pollen allergens in an area located outside of the current distribution range of Ambrosia". Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii 35 (1): 83-89. doi:10.5114/ada.2018.73167.

Harvard

Grewling, Ł., Jenerowicz, D., Bogawski, P., Smith, M., Nowak, M., Frątczak, A.,  and Czarnecka-Operacz, M. (2018). Cross-sensitization to Artemisia and Ambrosia pollen allergens in an area located outside of the current distribution range of Ambrosia. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 35(1), pp.83-89. https://doi.org/10.5114/ada.2018.73167

MLA

Grewling, Łukasz et al. "Cross-sensitization to Artemisia and Ambrosia pollen allergens in an area located outside of the current distribution range of Ambrosia." Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, vol. 35, no. 1, 2018, pp. 83-89. doi:10.5114/ada.2018.73167.

Vancouver

Grewling Ł, Jenerowicz D, Bogawski P, Smith M, Nowak M, Frątczak A et al. Cross-sensitization to Artemisia and Ambrosia pollen allergens in an area located outside of the current distribution range of Ambrosia. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2018;35(1):83-89. doi:10.5114/ada.2018.73167.

Introduction: The role of long-distance transported (LDT) Ambrosia pollen in inducing new sensitization and affecting sensitization rates in Artemisia-sensitized patients is unclear.

Aim: The aim of this study was to estimate the degree of cross-sensitization to Ambrosia/Artemisia allergens in citizens of Poznan (Western Poland). This area is covered by extensive Artemisia populations but does not currently have local Ambrosia populations.

Material and methods: Sera of 119 patients were tested by fluoroenzyme immunoassay (CAP-FEIA system) against pollen allergen extracts of Artemisia vulgaris and Ambrosia artemisiifolia, an allergenic component of A. vulgaris (nArt v 1), and an allergenic component of A. artemisiifolia (nAmb a 1). Skin prick tests (SPTs, n = 86) were performed with pollen allergen extracts of A. vulgaris and A. artemisiifolia. Artemisia and Ambrosia pollen in ambient air was collected (1996–2013) by a Hirst type volumetric trap sited at roof level (33 m).

Results: The SPT showed that the prevalence of sensitization to Ambrosia and Artemisia pollen exceeded 3.5%, and 10.5%, respectively. The measurements of IgE in blood serum (CAP-FEIA) revealed that among Ambrosia-sensitized patients 90.1% (20/22 patients) were concomitantly sensitized to Artemisia. 59.1% (13/22) of these patients reacted to nArt v 1, suggesting primary sensitization to Artemisia pollen. Only 2 (9.1%) patients were mono-sensitized to Ambrosia pollen extract, but surprisingly not to nAmb a 1.

Conclusions: The LDT Ambrosia pollen had a negligible effect on the rate of sensitization to Ambrosia allergens in Poznan and did not increase the prevalence of sensitization to Artemisia pollen in this region. However, the majority of patients showing hypersensitization to Artemisia pollen might also present symptoms during elevated episodes of LDT of Ambrosia pollen.

keywords:

Cross-sensitization to Artemisia and Ambrosia pollen allergens in an area located outside of the current distribution range of Ambrosia

Łukasz Grewling , Dorota Jenerowicz , Paweł Bogawski , Matt Smith , Małgorzata Nowak , Agata Frątczak , Magdalena Czarnecka-Operacz

Amb a 1, Art v 1, immunoglobulin E (IgE), skin prick test, fluorescence-linked immunosorbent assay

Łukasz Grewling

,

Dorota Jenerowicz

,

Paweł Bogawski

,

Matt Smith

,

Małgorzata Nowak

,

Agata Frątczak

,

Magdalena Czarnecka-Operacz