Cushing’s syndrome as a rare manifestation of adrenal tumours in infants – case report

Jagoda Badurowicz; Joanna Stefanowicz; Michalina Jezierska; Aleksandra Janecka; Dorota Birkholz-Walerzak; Andrzej Gołębiewski; Maciej Piskunowicz; Dominik Świętoń

doi:10.5114/polp.2019.89869

eISSN: 2300-8660
ISSN: 0031-3939

Pediatria Polska - Polish Journal of Paediatrics

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5/2019
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abstract:

Case report

Cushing’s syndrome as a rare manifestation of adrenal tumours in infants – case report

Jagoda Badurowicz

¹

,

Joanna Stefanowicz

^{1, 2}

,

Michalina Jezierska

^{1, 2}

,

Aleksandra Janecka

^{1, 2}

,

Dorota Birkholz-Walerzak

^{3, 4}

,

Andrzej Gołębiewski

⁵

,

Maciej Piskunowicz

^{6, 7}

,

Dominik Świętoń

^{6, 7}

Department of Paediatrics, Haematology, and Oncology, University Clinical Centre, Gdansk, Poland
Department of Paediatrics, Haematology, and Oncology, Faculty of Medicine, Medical University of Gdansk, Poland
Department of Paediatrics, Diabetology, and Endocrinology, Faculty of Medicine, Medical University of Gdansk, Poland
Department of Paediatrics, Diabetology, and Endocrinology, University Clinical Centre, Gdansk, Poland
Department of Surgery and Urology for Children and Adolescents, Faculty of Medicine, Medical University of Gdansk, Poland
Department of Radiology, Faculty of Health Sciences, Medical University of Gdansk, Poland
Department of Radiology, University Clinical Centre, Gdansk, Poland

Pediatr Pol 2019; 94 (5): 332–336

DOI: https://doi.org/10.5114/polp.2019.89869

Online publish date: 2019/11/19

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We report a case of a six-week-old male infant with a congenital tumour of the left suprarenal gland. The tumour was diagnosed by ultrasound examination (USG) as a neonatal suprarenal mass. By the third month of life, the patient had typical signs of Cushing’s syndrome. Based on the results of hormonal tests and imaging studies (USG and MRI), an adrenocortical tumour was suspected. The patient could only be cured by surgery. Histopathological examination confirmed clinical diagnosis of an adrenocortical tumour. We concluded that Cushing’s syndrome may be a rare clinical manifestation of adrenal tumour in neonates. Only careful observation allows for proper diagnosis and appropriate treatment. Correct diagnosis is essential for optimal postnatal treatment.

keywords:

Cushing’s syndrome as a rare manifestation of adrenal tumours in infants – case report

Jagoda Badurowicz 1 , Joanna Stefanowicz 1, 2 , Michalina Jezierska 1, 2 , Aleksandra Janecka 1, 2 , Dorota Birkholz-Walerzak 3, 4 , Andrzej Gołębiewski 5 , Maciej Piskunowicz 6, 7 , Dominik Świętoń 6, 7

Cushing’s syndrome, infant, suprarenal tumour

Jagoda Badurowicz

¹

,

Joanna Stefanowicz

^{1, 2}

,

Michalina Jezierska

^{1, 2}

,

Aleksandra Janecka

^{1, 2}

,

Dorota Birkholz-Walerzak

^{3, 4}

,

Andrzej Gołębiewski

⁵

,

Maciej Piskunowicz

^{6, 7}

,

Dominik Świętoń

^{6, 7}