How we can modify the risk of breast cancer?

Monika Zbucka; Monika Leśniewska; Paweł Knapp; Sławomir Wołczyński

eISSN: 2299-0038
ISSN: 1643-8876

Menopause Review/Przegląd Menopauzalny

Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

6/2005
vol. 4

Send email

Copy url:

abstract:

How we can modify the risk of breast cancer?

Monika Zbucka

,

Monika Leśniewska

,

Paweł Knapp

,

Sławomir Wołczyński

Prz Menopauz 2005; 6: 70-75

Online publish date: 2005/12/28

View full text Get citation

The multi-step process of carcinogenesis can be delayed, arrested or reversed by natural or synthetic agents. There are several independent risk factors for breast cancer development. Estimation of a women’s risk for breast cancer development is essential to identifying women who are most likely to benefit from chemoprevention. Treatment options for women who were at risk include increased surveillance, chemoprevention and prophylactic mastectomy.
In the National Surgical Adjuvant Breast and Bowel Project (NSABP) PI tamoxifen
treatment 20 mg/day resulted in a 49% and 50% reduction of invasive and non-invasive
breast cancer. Raloxifene is being evaluated in comparison with tamoxifen in the STAR study. The main outcome measure is breast cancer incidence and the results are expected in 2006.

keywords:

How we can modify the risk of breast cancer?

Monika Zbucka , Monika Leśniewska , Paweł Knapp , Sławomir Wołczyński

breast cancer, chemoprevention, tamoxifen, raloxifene

Monika Zbucka

,

Monika Leśniewska

,

Paweł Knapp

,

Sławomir Wołczyński