Determination of the criteria of early caries diagnostics in children of different ethnic groups domiciled in areas biogeochemically deficient in fluorine and iodine*

Aim of the study. To determine the criteria for early
diagnosis of carious lesions in children of different
ethnic groups permanently exposed to conditions of
fluorine and iodine deficiency. Materials and methods.
Microbial environment, biochemical parameters and
immunological status of saliva in 146 children aged 3-8
years were determined. The study subjects belonged
to different ethnic groups. Statistical evaluation of
the results was conducted. Results. Dependences of
biochemical parameters of microbial flora and local
immune characteristics of saliva were determined.
Correlation of dependence between pH of saliva,
content of ionized calcium and alkaline phosphatase
of Ck = 0.825, p<0.01 was also determined. Direct
correlation dependence between pH and phosphorus
content in the saliva from Ck = -0.876, p <0.01 has been
proven, which shows the inverse correlation dependence of intensity of caries and pH of saliva Ck = -0.09, p<0.01.
Conclusions. The following correlation dependences
have been proven: direct – between pH and phosphorus
content; inverse – between pH ionized calcium content
and alkaline phosphatase; between the intensity of
caries and pH; linear – between the concentration
of Streptococcus sobrinus and intensity of caries;
exponential – between sIgA concentration and
Streptococcus sobrinus; microflora and pH, alkaline
phosphatase and intensity of caries.