Difficulties in differentiating thin basement membrane disease from Alport syndrome

Jakub Żurawski; Paweł Burchardt; Monika Seget; Jerzy Moczko; Aldona Woźniak; Marcin Grochowalski; Wiesława Salwa-Żurawska

doi:10.5114/pjp.2016.65869

eISSN: 2084-9869
ISSN: 1233-9687

Polish Journal of Pathology

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4/2016
vol. 67

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abstract:

Original paper

Difficulties in differentiating thin basement membrane disease from Alport syndrome

Jakub Żurawski

,

Paweł Burchardt

,

Monika Seget

,

Jerzy Moczko

,

Aldona Woźniak

,

Marcin Grochowalski

,

Wiesława Salwa-Żurawska

Pol J Pathol 2016; 67 (4): 357-363

DOI: https://doi.org/10.5114/pjp.2016.65869

Online publish date: 2017/02/10

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We examined a group of 83 patients (57 children and 26 adults) with thin basement membrane disease and 17 patients with Alport syndrome. We compared the clinical data and, above all, the morphological patterns of both disease entities, with particular focus on not very advanced changes which might lead to a misdiagnosis due to the non-detection of the early stages of Alport syndrome.

keywords:

Difficulties in differentiating thin basement membrane disease from Alport syndrome

Jakub Żurawski , Paweł Burchardt , Monika Seget , Jerzy Moczko , Aldona Woźniak , Marcin Grochowalski , Wiesława Salwa-Żurawska

thin basement membrane disease, Alport syndrome

Jakub Żurawski

,

Paweł Burchardt

,

Monika Seget

,

Jerzy Moczko

,

Aldona Woźniak

,

Marcin Grochowalski

,

Wiesława Salwa-Żurawska