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eISSN: 2084-9893
ISSN: 0033-2526
Dermatology Review/Przegląd Dermatologiczny
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SCImago Journal & Country Rank
1/2024
vol. 111
 
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abstract:
Case report

Drug-induced subacute cutaneous lupus erythematosus initially diagnosed as erythema annulare centrifugum

Arletta Kozłowska
1
,
Aleksander Obtułowicz
1
,
Aleksandra Pizun
1
,
Joanna Radzimowska-Dudek
1
,
Agata Staroń
1
,
Grzegorz Dyduch
2
,
Bartosz Obtułowicz
3
,
Anna Wojas-Pelc
1

  1. Department of Dermatology, Jagiellonian University Medical College, Krakow, Poland
  2. Department of Pathomorphology, Jagiellonian University Medical College, Krakow, Poland
  3. Students’ Research Association, Chair of Dentistry, Jagiellonian University Medical College, Krakow, Poland
Dermatol Rev/Przegl Dermatol 2024, 111, 52-58
Online publish date: 2024/06/28
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Introduction:
An undesirable consequence of modern medicine and pharmacology is the occurrence of drug reactions. Drug-induced cutaneous reactions account for approximately 70% of all clinical manifestations of adverse drug effects. This can be attributed to the fact that the skin, a signaling organ, is the largest body organ and exhibits significant metabolic/immunological activity.

Case report:
We present the case of a woman with drug-induced subacute cutaneous lupus erythematosus, primary diagnosed as erythema annulare centrifugum, who was hospitalized in the in the Department of Dermatology.

Conclusions:
Knowing that the prevalence of drug-induced subacute cutaneous lupus erythematosus appears to be considerably higher (70%) than previously estimated (20%), the diagnosis of drug-induced subacute cutaneous lupus erythematosus should also be considered when idiopathic subacute cutaneous lupus erythematosus is suspected, particularly if several therapeutics are utilized in patients older then 60 years.

keywords:

diagnostics, autoimmune diseases, drug reactions, subacute cutaneous lupus erythematosus, erythema annulare centrifugum



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