Early and long-term outcomes of bioresorbable vascular scaffolds in the treatment of patients with coronary artery disease in real-world clinical practice – insights from the ZABRZE-BVS registry

Jacek Piegza; Piotr Desperak; Jacek Kowalczyk; Marek Gierlotka; Michał Hawranek; Piotr Chodór; Marcin Świerad; Andrzej Lekston; Zbigniew Kalarus; Mariusz Gąsior

doi:10.5114/aic.2018.79864

eISSN: 1897-4295
ISSN: 1734-9338

Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej

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abstract:

Original paper

Early and long-term outcomes of bioresorbable vascular scaffolds in the treatment of patients with coronary artery disease in real-world clinical practice – insights from the ZABRZE-BVS registry

Jacek Piegza

,

Piotr Desperak

,

Jacek Kowalczyk

,

Marek Gierlotka

,

Michał Hawranek

,

Piotr Chodór

,

Marcin Świerad

,

Andrzej Lekston

,

Zbigniew Kalarus

,

Mariusz Gąsior

Adv Interv Cardiol 2018; 14, 4 (54): 338–346

DOI: https://doi.org/10.5114/aic.2018.79864

Online publish date: 2018/12/11

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AMA

Piegza J, Desperak P, Kowalczyk J, et al. Early and long-term outcomes of bioresorbable vascular scaffolds in the treatment of patients with coronary artery disease in real-world clinical practice – insights from the ZABRZE-BVS registry. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2018;14(4):338-346. doi:10.5114/aic.2018.79864.

APA

Piegza, J., Desperak, P., Kowalczyk, J., Gierlotka, M., Hawranek, M.,  & Chodór, P. et al. (2018). Early and long-term outcomes of bioresorbable vascular scaffolds in the treatment of patients with coronary artery disease in real-world clinical practice – insights from the ZABRZE-BVS registry. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, 14(4), 338-346. https://doi.org/10.5114/aic.2018.79864

Chicago

Piegza, Jacek, Piotr Desperak, Jacek Kowalczyk, Marek Gierlotka, Michał Hawranek, Piotr Chodór,  and Marcin Świerad et al. 2018. "Early and long-term outcomes of bioresorbable vascular scaffolds in the treatment of patients with coronary artery disease in real-world clinical practice – insights from the ZABRZE-BVS registry". Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej 14 (4): 338-346. doi:10.5114/aic.2018.79864.

Harvard

Piegza, J., Desperak, P., Kowalczyk, J., Gierlotka, M., Hawranek, M., Chodór, P., Świerad, M., Lekston, A., Kalarus, Z.,  and Gąsior, M. (2018). Early and long-term outcomes of bioresorbable vascular scaffolds in the treatment of patients with coronary artery disease in real-world clinical practice – insights from the ZABRZE-BVS registry. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, 14(4), pp.338-346. https://doi.org/10.5114/aic.2018.79864

MLA

Piegza, Jacek et al. "Early and long-term outcomes of bioresorbable vascular scaffolds in the treatment of patients with coronary artery disease in real-world clinical practice – insights from the ZABRZE-BVS registry." Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, vol. 14, no. 4, 2018, pp. 338-346. doi:10.5114/aic.2018.79864.

Vancouver

Piegza J, Desperak P, Kowalczyk J, Gierlotka M, Hawranek M, Chodór P et al. Early and long-term outcomes of bioresorbable vascular scaffolds in the treatment of patients with coronary artery disease in real-world clinical practice – insights from the ZABRZE-BVS registry. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2018;14(4):338-346. doi:10.5114/aic.2018.79864.

Introduction
Randomized trials have proven the feasibility and safety of the bioresorbable vascular scaffold (BVS) in selected populations of patients. Data concerning the results of BVS in “real-world” registries with an appropriate sample size are limited.

Aim
Assessment of early- and long-term outcomes of patients undergoing bioresorbable scaffold implantation in an all-comers population of the ZABRZE-BVS registry.

Material and methods
The ZABRZE-BVS registry is a prospective registry including consecutive patients treated in the period 2013–2016 with the intention to implant a BVS (ABSORB, Abbott Vascular, Santa Clara, California). The primary endpoint was occurrence of the 12- and 24-month device-oriented composite endpoint (DoCE) defined as cardiac death, target-vessel myocardial infarction (TV-MI) or target lesion revascularization (TLR). The secondary endpoint includes occurrence of patient-oriented composite endpoint (PoCE) at 12 and 24 months, device (lesion basis) and procedural success (patient basis).

Results
A total of 456 patients during 467 procedures received 588 scaffolds in 563 lesions. Of note, 25.4% of patients presented with diabetes mellitus and 62.3% had an acute coronary syndrome. In QCA analysis, 78.7% of patients had type B2/C lesions, minimal lumen diameter was 0.78 ±0.54 mm, whereas post-procedural acute lumen gain was 1.61 ±0.61 mm. Median follow-up was 781 days. The cumulative rate of DoCE was 6.7% at 12 months and 12.2% at 24 months. Rates of 12- and 24-month PoCE were 12.4% and 20.1%, respectively. The percentage of device success was 98.7%, while the procedural success rate was 96.9%.

Conclusions
The Absorb BVS was successfully and safely implanted in an unselected group of patients. Scaffold thrombosis developed predominantly in patients with acute coronary syndrome (ACS).

keywords:

Early and long-term outcomes of bioresorbable vascular scaffolds in the treatment of patients with coronary artery disease in real-world clinical practice – insights from the ZABRZE-BVS registry

Jacek Piegza , Piotr Desperak , Jacek Kowalczyk , Marek Gierlotka , Michał Hawranek , Piotr Chodór , Marcin Świerad , Andrzej Lekston , Zbigniew Kalarus , Mariusz Gąsior

bioresorbable vascular scaffold, coronary percutaneous intervention, long-term survival

Jacek Piegza

,

Piotr Desperak

,

Jacek Kowalczyk

,

Marek Gierlotka

,

Michał Hawranek

,

Piotr Chodór

,

Marcin Świerad

,

Andrzej Lekston

,

Zbigniew Kalarus

,

Mariusz Gąsior