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2/2023
vol. 76 abstract:
Original paper
Effectiveness of four home oral care products for primary enamel re-mineralization with early carious lesion: an in-vitro study
Faranak Razmjouei
1
,
Mahtab Memarpour
1
,
Farshid Fathi
2
J Stoma 2023; 76, 2: 77-83
Online publish date: 2023/06/26
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Introduction
Management of dental caries during early stages is considered a clinical problem in young children. Objectives The current in-vitro study assessed the influence of four home oral care products on re-mineralization of early caries lesions using enamel micro-hardness (EMH) test and morphological changes with scanning electron microscopy (SEM). Material and methods Sixty primary canine teeth were selected and randomly divided into 5 groups (n = 12 in each group). Samples were de-mineralized, and toothpaste slurries were prepared to treat de-mineralized enamel with a pH-cycling model. The groups were divided as follows: Group 1. Control (no intervention); Group 2. Fluoridated toothpaste; Group 3. Tooth mousse containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP); Group 4. Toothpaste containing bio-active glass and fluoride; Group 5. Tooth cream containing nano-hydroxyapatite, fluoride, and xylitol. EMH was evaluated in fifty specimens (each group, n = 10) at three times: before and after de-mineralization, and after 28 days of pH-cycling and treatment. Two samples from each group were observed with scanning electron microscopy (SEM). Data were analyzed with multiple-sample repeated measures ANOVA and Tukey’s HSD post-hoc tests (p < 0.05). Results There was a significant difference in EMH between mean baseline values and de-mineralized enamel (p < 0.001). Re-mineralization significantly increased EMH in all treatment groups (p < 0.001). In group 5, the percent of EMH recovery was significantly greater than in other groups (p < 0.001). There were significant differences among the other three treatment groups (all p < 0.001). SEM images showed minerals deposited on the dissolved prismatic enamel in all groups. Conclusions The nano-hydroxyapatite-based tooth cream was the most effective home oral care product for re-mineralization of primary tooth enamel. keywords:
bio-active glass, casein phosphopeptide-amorphous calcium phosphate, dental caries, fluoride, nano-hydroxyapatite, primary enamel, re-mineralization |